Off-the-shelf T-cell therapy from gene edited stem cells
Dr Jo Brewer outlines research into allogeneic products by gene editing stem cells, which has the potential to build a broad family of multiple immune cell types, including T-cell therapies.
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Dr Jo Brewer outlines research into allogeneic products by gene editing stem cells, which has the potential to build a broad family of multiple immune cell types, including T-cell therapies.
Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
Researchers have developed a vaccine using stem cells that protected mice injected with pancreatic cancer cells from developing tumours.
Researchers have shown that Chroman 1, Emricasan and trans-ISRIB, in combination with polyamines, are effective at protecting induced pluripotent stem cells from stress.
Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
An international collaboration has led to the development of monkey embryos able to grow with injected human stem cells.
A team has developed a lotus-root-shaped construct to deliver iPSC-derived pancreatic beta-cells to patients with type I diabetes mellitus.
Sequencing and transcriptome data on iPSCs has been used to identify correlations between genetic variants and expression patterns.
CRISPR-Cas9 and stem cell technologies have been used to create a cellular model of acute myeloid leukaemia, revealing therapeutic targets.
A team has developed enterocyte-like cells from hiPSCs, which can be used to study the absorption of novel oral drugs.
Researchers have uncovered a flaw in lab models used to study the human blood-brain barrier and a potential strategy to correct the error.
Using a new compound mixture, researchers have created adaptive and regenerative stem cells from human fat cells.
A new technique using CRISPR has been developed by researchers to identify programmed stem cells that mature into neuronal cells.
Researchers have used small molecule neural precursor cells to develop midbrain organoids that enable drug effects to be assessed in a complex cell environment.
By editing out a set of proteins on the surface of human pluripotent stem cells, researchers have ensured they will be not be rejected by the body's immune system.