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New technique improves the selectivity of kinase inhibitors
11 September 2015 | By Victoria White
The new technique could cut the potential for side effects and help usher kinase inhibitors past strict regulatory hurdles...
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Investigation of venom use in stem cell differentiation
Stem cells differentiate to form more than 200 specialised cells, including erythroid bodies, haematopoietic cells, myogenic cells, neural cells, signalling cells and structural cells, such as hepatocytes. Differentiation of stem cells triggers a number of variable changes in the cell, such as membrane potential, responsiveness to signal, metabolic activities, and…
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Novel approaches to targeting protein tyrosine kinases
Protein kinases, a diverse group of cellular enzymes, play fundamental roles in maintaining normal cellular functions such as growth, cell cycle control, proliferation, differentiation, migration, cellular survival and apoptotic induction.