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Lipids

Neurological physical examination of motor neurone diseases. Doctor neurologist checks the status of the patient's reflexes in office in hospital.

news

Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells

21 June 2022 | By Ria Kakkad (Drug Target Review)

A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.

3d illustration of T cells or cancer cells

news

Researchers identify pathway that regulates lipid synthesis and contributes to tumour survival

12 May 2022 | By Ria Kakkad (Drug Target Review)

In their latest study, researchers at Moffitt Cancer Center have shown that cancer cells in an acidic environment undergo lipid synthesis and accumulation.

news

University at Buffalo to develop drugs that stop ovarian cancer from feeding on fat

28 April 2022 | By Ria Kakkad (Drug Target Review)

The University at Buffalo has received a $2.3 million grant from the US National Cancer Institute to identify metabolic vulnerabilities of ovarian cancer and to develop potential treatments for the disease.

Multiple sclerosis nerve disorder and damaged myelin or MS autoimmune disease with healthy nerve with exposed fibre with scarred cell sheath loss with 3D illustration elements.

news

Reducing sclerosis inflammation in mice

27 April 2022 | By Ria Kakkad (Drug Target Review)

Researchers have been able to reduce the chronic inflammation associated with multiple sclerosis in a mice model of the disease, by administering one of the resolving lipid mediators of inflammation, Maresin-1.

Image showing 3D illustration of human lungs

news

New study highlights the possibility to target gene editing in the lungs

18 March 2022 | By Ria Kakkad (Drug Target Review)

Researchers have been able to significantly reduce tumours in a pre-clinical model of a rare genetic lung disease.

news

Antibacterial molecules show promise against antibiotic-resistant bacteria

18 November 2021 | By Anna Begley (Drug Target Review)

The new group of molecules can be chemically altered, showing potential for the development of effective antibiotics with few side effects.

Patient with amyotrophic lateral sclerosis receiving physiotherapy

news

Altered fat metabolism shown to play a key role in ALS

17 November 2021 | By Anna Begley (Drug Target Review)

Scientists reveal that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis.

news

MIT study reveals how lipid imbalance affects cancer growth in mice

21 October 2021 | By Anna Begley (Drug Target Review)

In a new study, a calorie-restricted diet significantly reduced tumour growth in mouse models, suggesting new possibilities for cancer therapies.

news

Eczema may stem from poorly regulated sex hormones, study finds

20 September 2021 | By Anna Begley (Drug Target Review)

A breaking discovery has revealed the gene HSD3B1 that regulates the production of sex hormones is linked to atopic dermatitis (AD).

news

S1P may be a potential target for cerebral blood alterations

9 September 2021 | By Anna Begley (Drug Target Review)

Sphingosine-1 phosphate was found to regulate blood glow in cerebral blood vessels in mice, presenting a potential therapeutic target.

news

Quantifying method developed to improve neurodegeneration studies

18 August 2021 | By Anna Begley (Drug Target Review)

Researchers have created a new method to quantify protein droplets involved in neurodegenerative diseases, enhancing the study of treatments.

news

CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study

17 August 2021 | By Anna Begley (Drug Target Review)

CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.

news

Greasy hair proves to be an unexpected possibility for obesity treatment

30 July 2021 | By Anna Begley (Drug Target Review)

Researchers have revealed that the immune system of obese mice treated with TSLP released lipids through sebaceous glands.

news

Very long-chain fatty acids found to block SARS-CoV-2 infection

11 June 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that omega-3 very long-chain polyunsaturated fatty acids can block SARS-CoV-2 and protect lung cells.

news

Lipid droplets may prevent kidney damage from high-fat diets

17 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown in fruit flies that lipid droplets could prevent the kidney damage that leads to chronic kidney disease.

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Lipids