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Metabolic collaboration linked to Alzheimer’s disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
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Metabolomics
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Metabolism can be used to subtype hepatoblastoma
Scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma...
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New biomarker shows promise for rare metabolic diseases
Researchers have discovered a new biomarker associated with a rare metabolic disorder may facilitate better diagnosis and identification of new drugs...
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Metabolic markers accurately diagnose typhoid fever
Researchers have identified a metabolite 'signature' that can accurately distinguish typhoid from other fever-inducing tropical diseases using patient blood samples.
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New method for early screening of colorectal cancer
A highly sensitive method that can detect even the earlier stages of colorectal cancer has been developed by researchers in Japan.
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Nimbus Therapeutics enters into strategic partnership with Charles River Laboratories to advance new therapeutic programs
Nimbus Therapeutics and Charles River Laboratories International, Inc. (NYSE: CRL) launched a multi-year strategic partnership to advance new programs spanning the disease areas of immunology, metabolic disorders and oncology from the discovery phase through to Investigational New Drug (IND) submission.
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New discovery to identify Huntington’s disease before symptoms appear
Early warning signs of Huntington’s disease have been uncovered in sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study has found.
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The next revolution in stratified medicine: molecular phenotyping with metabolomics
The study of biochemistry provides molecular insights into how the human population ages, how diseases commence and progress, how molecular changes relate to disease remission and relapse, and how humans respond to treatments...
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Omics In-Depth Focus 2016
Featured in this Omics In-depth Focus: The next revolution in stratified medicine-molecular phenotyping with metabolomics; Pharmacometabolomics as the key to personalised medicine...
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Pharmacometabolomics as the key to personalised medicine
Blanketed administration of drugs to all populations assumes that all patients respond similarly. Despite pharmaceutical companies’ efforts to develop drugs with large therapeutic windows, there are often and inevitably subpopulations of individuals who will either not respond to therapy or will respond with adverse effects...
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Identifying targets in MYC-driven triple-negative breast cancer
12 May 2016 | By Victoria White, Digital Content Producer
Dr Andrei Goga of UC San Francisco has taken a multi-faceted approach to identifying new therapeutic targets in MYC-driven triple-negative breast cancers...
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Researchers investigate defects in the DJ1 gene in Parkinson’s
2 March 2016 | By Victoria White
Researchers looked at the metabolism of neurons lacking DJ1 and discovered that two key metabolic pathways are affected...