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New Gut Cell Atlas reveals genetic origins of Crohn’s disease
The Gut Cell Atlas comprises 428,000 cells in the gut and sheds light on the origin of Crohn’s disease and other intestinal diseases.
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Microbiology
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Detergent-like APOL3 protein shown to kill bacteria in human cells
Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.
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Scientists develop novel strategy for tuberculosis vaccine
A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.
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New study may improve enzyme replacement therapy for Pompe patients
Researchers have developed a new method that could make enzyme replacement therapy more efficient for Pompe disease treatment.
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New study discovers how Parkinson’s-linked protein attacks mitochondria
Researchers have used fruit fly larvae to explore how alpha-synuclein impacts the mitochondria, advancing the study of Parkinson’s disease.
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Researchers reveal how microbiome bacteria adapt through transmission
Scientists have used genetic sequencing to demonstrate how the transmission of gut bacteria influences its evolution and functions, which could effect human health.
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Artificial intelligence may reveal how microbiome affects vaccine response
Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.
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Prize winner uncovers how microbiome can combat neurodegeneration
Eran Blacher has won the NOSTER & Science Microbiome Prize for discovering the link between the microbiome and neurodegenerative diseases.
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Genes behind antibiotic activity in bacteria uncovered by metabologenomics
Researchers have used comparative metabologenomics to uncover what may be “silencing” bacteria to produce desirable compounds.
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Metabolite could defend against harmful intestinal bacteria, study shows
Acetate was found to be involved in regulating complex microbes and could help trigger an immune response against harmful bacteria in mice.
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Intestinal bacteria found to produce SARS-CoV-2-inhibiting compounds
Researchers have screened bacteria in the gut, finding that Bifidobacteria have inhibitory activity against SARS-CoV-2.
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Mass spec method developed to identify drugs to fight resistant bacteria
Researchers have developed a native state mass spectrometry technique to identify inhibitors of the bacterial protein metallo-beta-lactamase.
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Researchers use exosomes to develop potential salmonella vaccine
Exosomes containing salmonella antigens were administered to the mice, enabling the models to develop antibodies against the bacteria.
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AI platform developed to reveal how bacteria infect intestines
A new artificial intelligence (AI) method has been created to uncover which proteins enable bacteria to infect human intestines.
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Drug development platform could provide targeted antimicrobials
Researchers have developed a platform named FAST to produce antibiotics that specifically target just the bacteria of interest.
