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Role of retrons in bacteria revealed, with potential for use in gene editing
The role that retrons in bacteria has been discovered by researchers, who found they protect colonies when infected by viruses.
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Microbiology
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Adding to the arsenal: targeting human proteins for controlling M. tuberculosis growth
The National Institute of Health envisions a plan for managing tuberculosis in the 21st century. Included in this proposal is targeting host proteins as an add-on therapy to antibiotics. Infectious disease biologists are focusing on this strategy and it is a topic of active research. Recently, a multinational research team…
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Imaging and machine learning system created to discover tuberculosis drugs
Researchers have developed MorphEUS, a technology to identify new drugs that combat M. tuberculosis by revealing how compounds destroy the bacteria.
webinar
Drug repurposing approaches to fast track development of new therapies for COVID-19
26 June 2020 | By Tecan
This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.
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Screening reveals rocaglate compounds kill C. auris
Researchers have screened over 2,000 compounds to discover that rocaglates effectively combat C. auris, offering a potential new treatment.
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CRISPR discovery could be used to combat multi-drug resistant bacteria
A study has shown that plasmids use type IV CRISPR-Cas against competing plasmids, leading the researchers to suggest the method as a novel way to tackle multi-drug resistant bacteria.
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Cannabidiol identified as potential ‘helper’ compound for antibiotics
Researchers have found that using antibiotics in combination with cannabidiol (CBD) enhanced their effect against Staphylococcus aureus bacteria.
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CRISPR-Cas3 used to combat C. difficile in lab and mice
Researchers have shown that CRISPR-Cas3 can successfully attack C. difficile in vitro and in mice, by causing DNA damage to the pathogen.
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Compound combination successful against Pseudomonas aeruginosa
Researchers have developed a new combination of compounds called AB569 which has demonstrated success at fighting deadly pathgoens like Pseudomonas aeruginosa.
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Smart bioprocessing with the new Eppendorf control system
Flexible and intuitive operation of a wide range of biological processes with the SciVario® twin bioreactor control system.
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Class of antibiotics with unique mechanism to combat bacteria discovered
Researchers have uncovered new antibiotics which prevent bacteria from multiplying, offering a strategy to fight infections.
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Phage-enriched mucosal surfaces could combat bacteria infections
Researchers have found that, in rainbow trout models, phages on mucosal surfaces infect pathogenic bacteria, providing protection.
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Researchers discover potent new antimicrobial molecule
A compound that has antimicrobial properties has been found by researchers, which could be used to combat drug-resistant infections.
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Lung response to bacteria revealed by researchers
A study has discovered the process behind the lung immune response, which could be used to develop treatments against pneumonia.
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T-box and tRNA complex structure revealed by study
A team of researchers has uncovered the structure of a T-box regulatory mechanism in bacteria, which could aid in the development of novel antibiotics.