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Potential antibiotic alternative discovered within bacteria
A study has revealed an enzyme in bacteria that produces a molecule which is toxic to other bacteria and shows promise as an antibiotic substitute.
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Microbiology
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Mucus has been shown to tame microbes in new study
Glycans, which are found in mucus, have the ability to regulate how microbes behave and could lead to new therapeutics.
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HIV infant model opens new avenues for research
An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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Realising the promise of laboratory automation in biomedical research
Automation offers a choice of powerful ways to design and execute high-quality laboratory research. The use of lab automation is now pervasive in biomedical labs, offering versatile platforms on which to perform an ever‑expanding array of tasks free of human errors, and a unique means to address the problems associated…
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New cancer drug targets accelerate path to precision medicine
Researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival...
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Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours
Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
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MicroRNA regulates drug tolerance in subset of lung cancers
Newly identified pathway offers promising targets for preventing tumour relapse...
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Scientists decipher 3D structure of promising molecular target for cancer treatment
Columbia University discovery could be a major step in developing therapies for cancer, controlling cholesterol...
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Creating blood vessels on demand
A new study shows that stable angiogenesis can be achieved by simply injecting a hydrogel with mechanical properties resembling that of a blood clot...
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Tongue microbiome could help to detect early-stage pancreatic cancer
The bacteria living in the tongue's microbiome could provide an insight into an individuals heath, and may help to detect pancreatic cancer earlier...
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Investigating tumour microenvironments for more effective treatments
Tumour microenvironments give insights into more effective therapies against lung cancer, a bigger killer than colon, prostrate and breast cancers combined...
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Study identifies strain of bacteria as a risk factor for stomach cancer
Researchers have found a specific strain of Helicobacter pylori strongly correlated with stomach cancer...
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Researchers report success culturing Treponema pallidum, which causes syphilis
Researchers have described a new method for culturing Treponema pallidum, that until now it couldn't be cultured in a lab dish...
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Sensitive new assay detects hepatitis B infection in single liver cells and serum
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...