news
Discovery of novel mechanism for MRSA virulence
US researchers revealed that MRSA has undergone repeated mutations in the sarZ gene, leading to increased severity of blood stream infections in mouse models.
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Microbiome
news
Does treating adolescent acne with systemic antibiotics have unintended consequences on the skeleton?
US researchers unmask the consequences of treating adolescent acne with systemic antibiotics; as it can lead to altered profiles of circulating bile acids that reduce osteoblast function and bone mass accrual.
news
Bacteria in a tumour’s microbiome could influence how cancer responds to treatment
US researchers find that bacteria could help tumours progress and resist treatment.
news
Researchers make progress towards CRISPR-based microbiome editing
US researchers have engineered bacteriophages to deliver CRISPR-Cas payloads for targeted editing of a bacterium.
podcasts
Episode 11 – CRISPR with Dr Jakob Haaber, SNIPR Biome & Dr Richard Fox, Infinome Biosciences
Join leading experts as they discuss the wide range of uses for CRISPR, including for therapeutics and biomanufacturing.
news
IgG antibodies in breast milk help shape infants’ gut bacteria and immunity
A new study in mice has highlighted that gut beneficial bacteria can be transferred from mothers to infants through breast milk and help infants defend against infection-induced diarrheal illness.
news
Dietary fibre in the gut could help with skin diseases
New research has found that microbial fermentation of dietary fibre in the gut can protect against allergic skin diseases.
news
Gut bacteria may contribute to blood pressure drug resistance
By studying the gut microbes of rats, researchers discovered that a bacteria known as Coprococcus comes contributes to resistance to high blood pressure drugs.
news
Previous studies of human microbiome may be biased in favour of Global North
A new study has suggested that previous global research into the human microbiome is heavily biased in favour of wealthy countries such as the US and UK.
news
Gut-brain pathway metabolite involved in age-related cognitive decline, study shows
In mice, researchers have shown that δ-valerobetaine plays a role in neurocognitive ability, making the metabolite a target for age-related memory loss.
article
Analysing proteomics data to translate in vivo studies as early as possible
Dr Antal Szalay, CEO and Founder of Ultimate Medicine, explores how the analysis of omics data, especially metabolomics and proteomics, can provide researchers with vital insight that can inform the development of drugs for conditions associated with age.
news
Scientists discover mechanism that links autism and intestinal inflammation
The new research shows how interleukin-17a (IL-17a) can alter the trajectory of immune system development and cause gut inflammation.
news
Machine learning models predict antibiotic resistance spread
Scientists have used several machine learning models to predict bacterial gene exchange, which could reveal novel antibiotic targets.
news
New antibiotic a possible alternative to treat Lyme disease
The antimicrobial hygromycin A was shown to clear Lyme disease in mice, representing a promising therapeutic against the disease.
news
New single-cell and metagenomic technique can characterise microbes
The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.