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Novel biomaterial could be used to accelerate bone regeneration
In lab conditions, a new biomaterial was able to accelerate bone regeneration by boosting an immune response that encourages repair.
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Novel pathway to target colorectal cancer identified
Researchers have found that PGE2, a signalling molecule involved in inflammation, promotes colorectal cancer progression through a microRNA and targeting that microRNA could have therapeutic potential.
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microRNA could lead to new methods to treat multiple sclerosis
In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.
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CNS tumour aggressiveness reduced with new molecule
A microRNA inhibitor has been identified which reduced the sizes of aggressive CNS tumours and improved survival in mice.
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New mechanism of controlling fat production revealed
A new study has shown a new mechanism of controlling fat production in the body which could lead to new therapies to treat obesity.
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New research advances the possibility of regenerating tissue after a heart attack
This research advances the possibility of reviving the heart's regenerative capacities using microRNAs.
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Engineered dl355 virus has the potential to be an effective anticancer treatment
An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers...
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Chromatin study unearths link between DNA-protein binding and cancer
A team of scientists led by Stanford University School of Medicine has identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes.
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miR-31 may help target treatments for Crohn’s patients
Researchers have pinpointed a single molecule - microRNA-31 (miR-31) - the levels of which predict whether a patient has subtype 1 or subtype 2 of Crohn's disease...
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Small molecule factors found to influence age-related bone deterioration
Scientists in the U.S. have reported findings about the mechanisms that contribute to the experience of weaker bones with age.
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Powerful molecules provide new findings about Huntington’s disease
Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...
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New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
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New biomarker provides personalised treatment options for bladder cancer
Researchers use data science and genomics to help determine best treatment options for specific bladder cancers...
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MicroRNA provides promise in search for simple, early test for Alzheimer’s
Researchers have found early evidence that tiny snippets of microRNA may help with early detection of conditions such as Alzheimer's disease...
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Bioactivity profiling supporting the progression of phenotypic hits
Addressing the optimisation of hits derived from a target-agnostic phenotypic screen, using a strategy based on combining bioactivity profiling and reference compound characterisation...