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In this issue: AI-driven automated chemistry as a tool to accelerate drug discovery processes, the shifting landscape of immuno-oncology, and how lipid molecules provide an insight into biological research.
A team of scientists in the UK have developed a fluorescent imaging probe capable of tracking Gram-negative bacterial lung infections in real time.
Researchers have combined an open source software programme and commercially available hardware to image neuron activity at high resolution...
The microscope slide is flat (2D), but the world around us is not – despite the flat-earth theories. We need volume information about our samples, ideally with high resolution in all three dimensions as well as over time – the fourth dimension...
Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.
Researchers at Baylor College of Medicine and Texas Children’s Hospital have identified unexpected new key players in the development of an early onset form of Parkinson’s disease called Parkinsonism.
Researchers have identified a link between a neurotransmitter imbalance and brain connectivity between regions of the brain that play a role in social communication and language.
A collaborative research team is on a quest to collapse a tiny pocket between cardiac cells, called the perinexus.
Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.
Researchers have developed a new form of microscopy that allows them to observe the formation and evolution of cell membrane focal adhesions…
In this issue the latest applications of molecular imaging in drug development are reviewed by Ben Burke and Steve Archibald and new horizons in 3D microscopy are explored by Dimitri Scholz and Karl Gaff.
The NIH is supporting efforts to broaden biomedical scientists’ access to cryo-electron microscopy the imaging method that is revolutionising structural biology...
The structure of teneurins, proteins involved in embryonic development and the nervous system, is more like bacterial toxins than any other human protein.
Research sheds light on the initial phase of infectious disease and potential for prevention of pneumococcal septicaemia...
Researchers have reconstructed the 3.1 Å structure of the herpes simplex virus type 2 (HSV-2) B-capsid and built the atomic model, thus expanding the understanding of the assembly mechanism of the capsid...
