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Microscopy

GSK: A Lifetime in Fluorescence

4 April 2017 | By Carl Haslam, Gabriella Clarke, Luke Greenhough, Peter D Craggs, Ryan P Bingham

GSK's top investigators explain why the data quality offered by Fluorescence lifetime detection technology for drug discovery applications is superior…

news

Muscle cryomicroscopy images could provide model for nanomachines

9 March 2017 | By Osaka University

Myosin provides model for nanomachines

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Nanoinjection increases survival rate of cells to 90%

2 March 2017 | By Niamh Marriott (Drug Target Review)

How do tumours grow? And how do bacteria transform harmless substances into medical agents? When biophysicists want to understand what is happening in living cells, they have to introduce fluorescent probes or other foreign molecules. There are several ways to overcome the cell wall without causing the cell permanent harm.

news

Diabetic research suggests purslane herb extract mimics insulin

20 December 2016 | By Niamh Marriott (Drug Target Review)

A new study has confirmed the anti-diabetic properties of the purslane herb extract Portulaca oleracea L.

news

How the anthrax toxin forms a deadly “conveyer belt”

28 September 2016 | By Niamh Louise Marriott, Digital Content Producer

During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...

news

Super-resolution microscopy reveals the surface of T cells

16 June 2016 | By Victoria White, Digital Content Producer

Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated using super-resolution microscopy...

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Snapshots of the NMDA receptor could aid drug development

3 May 2016 | By Victoria White, Digital Content Producer

Researchers have obtained images of the NMDA receptor in different states. Understanding how NMDA receptors activate is critical in designing new drugs...

news

Nanoparticles hold promise in the fight against genital herpes

28 April 2016 | By Victoria White, Digital Content Producer

Researchers have shown that zinc-oxide nanoparticles can prevent genital herpes virus from entering cells, and help natural immunity to develop...

article

Trends in contemporary microscopy

24 September 2015 | By Dimitri Scholz (University College Dublin), Jeremy Simpson (University College Dublin)

In the biomedical arena the imaging of biological samples has long been a mainstay technology, not only furthering our understanding of fundamental biology, but also playing a key role in designing strategies and therapies to combat infection and disease...

news

CLR01 targets HIV and prevents semen from promoting infection

18 August 2015 | By Victoria White

Researchers have discovered a small molecule, known as CLR01, that attacks the HIV virus and disrupts the amyloids in semen that promote HIV infection...

news

Researchers discover new type of mycovirus

28 July 2015 | By Victoria White

Researchers have discovered a completely new type of mycovirus that can infect the fungus Aspergillus fumigatus, which can cause the disease aspergillosis

news

Scientists use cryo-EM to image one of the central proteins of life

2 July 2015 | By Victoria White

Scientists have pioneered the use electron cryo-microscopy (cryo-EM) to picture in exquisite detail one of the central proteins of life...

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Microscopy