Molecular Biology

The European Life Sciences Community meets at BASEL LIFE

13 April 2018 | By BASEL Life Science

Leading experts of the European Life Sciences Community are engaging under the name BASEL LIFE to establish a bridge between science and business.

Mitra Biotech

The National Institutes of Health announce Biobanking Medical Project

9 April 2018 | By SMi Group

SMi Reports: The National Institutes of Health announce one of the most ambitious medical projects in biobanking, which will commence this spring.

Scientists discover new causes of cellular decline in prematurely aging children

21 March 2018 | By Drug Target Review

Researchers have uncovered new answers about why cells rapidly age in children with the rare and fatal disease, Hutchinson-Gilford Progeria Syndrome (HGPS).

Scientists develop novel method for membrane protein crystallisation

8 March 2018 | By Drug Target Review

Scientists in Switzerland have developed a new means of crystallising membrane proteins – a hitherto elusive feat – in order to study their structure and aid understanding of their processes.

Staphylococcus epidermidis may protect against skin cancer

2 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have reported a potential new role for some bacteria on the skin, protecting against cancer...

New insights into alpha-synuclein function holds promise for Parkinson’s treatment

19 February 2018 | By Drug Target Review

Researchers have gained important insights into the role of alpha-synuclein – the protein associated with Parkinson’s disease – in nerve cells and how calcium affects its function. This knowledge is hoped to better arm scientists regarding future treatment for the disease.

Study uncovers molecular events that reveal pathway toward heart disease therapy

14 February 2018 | By Drug Target Review

Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.

Novel classification can lead to new ways to diagnose and treat cancer

14 February 2018 | By Drug Target Review

A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.

Small molecule could make a big difference for arthritis patients

13 February 2018 | By Drug Target Review

Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.

Final numbers are in: 42 million protein molecules in a yeast cell

18 January 2018 | By Drug Target Review

Researchers have officially revealed the abundance of protein molecules in a single cell runs into the tens of millions: around 42 million, to be precise.

Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s

15 January 2018 | By Drug Target Review

A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.

NIH researchers report first 3D structure of DHHC enzymes

12 January 2018 | By Drug Target Review

The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.

Video: PerkinElmer signals lead discovery

3 January 2018 | By PerkinElmer

Quickly gain new insights into chemical and biomolecular research data. Featuring guided search and analysis workflows and dynamic data visualisations.

Proteogenomics research – on the frontier of precision medicine

14 December 2017 | By Alicia Landeira, Javier Carabias, Jonatan García, Manuel Fuentes (Cancer Research Centre), Maria Gonzalez-Gonzalez, Paula Díez (Cancer Research Centre), Rafael Góngora, Rodrigo Garcia-Valiente

Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.