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Researchers have gained important insights into the role of alpha-synuclein – the protein associated with Parkinson’s disease – in nerve cells and how calcium affects its function. This knowledge is hoped to better arm scientists regarding future treatment for the disease.
Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.
A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
Researchers have officially revealed the abundance of protein molecules in a single cell runs into the tens of millions: around 42 million, to be precise.
A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
Quickly gain new insights into chemical and biomolecular research data. Featuring guided search and analysis workflows and dynamic data visualisations.
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.
Manipulation of the sugar metabolism and associated modulation of the immune system could open up new options for treating specific infectious and also autoimmune diseases...
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
Long-term goal is to develop treatments that prevent cancer cells from attaching to new sites during metastasis.
