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Scientists discover new causes of cellular decline in prematurely aging children
Researchers have uncovered new answers about why cells rapidly age in children with the rare and fatal disease, Hutchinson-Gilford Progeria Syndrome (HGPS).
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Molecular Biology
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Scientists develop novel method for membrane protein crystallisation
Scientists in Switzerland have developed a new means of crystallising membrane proteins – a hitherto elusive feat – in order to study their structure and aid understanding of their processes.
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Staphylococcus epidermidis may protect against skin cancer
Researchers have reported a potential new role for some bacteria on the skin, protecting against cancer...
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New insights into alpha-synuclein function holds promise for Parkinson’s treatment
Researchers have gained important insights into the role of alpha-synuclein – the protein associated with Parkinson’s disease – in nerve cells and how calcium affects its function. This knowledge is hoped to better arm scientists regarding future treatment for the disease.
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Study uncovers molecular events that reveal pathway toward heart disease therapy
Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.
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Novel classification can lead to new ways to diagnose and treat cancer
A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.
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Small molecule could make a big difference for arthritis patients
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
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Final numbers are in: 42 million protein molecules in a yeast cell
Researchers have officially revealed the abundance of protein molecules in a single cell runs into the tens of millions: around 42 million, to be precise.
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Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s
A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
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NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
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Video: PerkinElmer signals lead discovery
Quickly gain new insights into chemical and biomolecular research data. Featuring guided search and analysis workflows and dynamic data visualisations.
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Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
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Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
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SBP scientists uncover mechanism for blood vessel regeneration
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.
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Immune system can be modulated by targeted manipulation
Manipulation of the sugar metabolism and associated modulation of the immune system could open up new options for treating specific infectious and also autoimmune diseases...