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Newly identified compound reduces potency of Shiga toxin
Scientists have identified a molecule that can bind to a lethal subtype of the bacterial Shiga toxin, suppressing its deadly effects.
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Molecular Biology
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Researchers halt the growth of multiple myeloma in mice
Scientists from Stanford University have been able to halt the growth of multiple myeloma and diffuse large B cell lymphoma in mice with custom molecule sBCMA-Fc V3.
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Researchers use graphene for same-time, same-position biomolecule isolation and sensing
The study has highlighted an important advance in using graphene for electrokinetic bio-sample processing and analysis.
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Chemokines work undercover as drivers of autoimmune disease
New research has uncovered a hitherto unknown mechanism whereby chemokines form DNA-bound nanoparticles that play a key role in autoimmune disorders.
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Scientists develop new graphene imaging technique for clearer pictures of small molecules
Scientists have created a new imaging technique with graphene which generates clearer pictures of the structures of small molecules.
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Key protein identified that helps turn pancreatic cancer cells into a more aggressive form
A new study has shown that it is possible to reverse key process that allows pancreatic cancer cells to grow and spread around the body.
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Immune molecules from a llama could provide protection against COVID-19
Researchers have shown that tiny, robust immune particles derived from a llama’s blood could provide strong protection against every COVID-19 variant.
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Scientists identify the molecular mechanisms behind learning and memory
Researchers identify how acetylcholine sets off a signal cascade in brain cells that directly influence aversive learning and memory formation. The findings may open door to new therapeutic strategies for Alzheimer’s disease.
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Promising anticancer molecule identified
Researchers have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
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NRG Therapeutics to develop small molecule disease-modifying medicines for debilitating chronic neurodegenerative disorders
NRG is developing a pipeline of brain-penetrant small molecule inhibitors of the mitochondrial permeability transition pore (mPTP) with potential as first-in-class treatments for Parkinson's disease and motor neuron disease.
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An effective and error-free gene editor
Scientists have developed a new gene editor which uses a modified pair of molecular scissors that make nicks on opposite strands of the DNA at two different points.
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Scientists discover new molecule that kills hard-to-treat cancers
Scientists have synthesised a new molecule that could kill a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.
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Spatial biology is the next life science revolution
Dr Richard Goodwin, Head of Imaging & AI, Clinical Pharmacology & Safety Sciences at AstraZeneca, explores the latest innovation in early therapeutic development – spatial biology.
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Novel microscopy technique to light the way towards new medicine
Researchers have developed a ground-breaking microscopy technique that allows proteins, DNA, and other tiny biological particles to be studied in their natural state in a completely new way.
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New discovery could lead to treatment for cardiac hypertrophy
Scientists have identified an important new mechanism that causes the heart’s muscle to thicken which markedly increases the risk of irregular heart rhythms and cardiac hypertrophy.