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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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Molecular Targets
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Small molecule could make a big difference for arthritis patients
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
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Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s
A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
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CXCR4 receptor provides therapeutic target for ovarian cancer
Researchers have described a key cellular receptor in the processes of metastasis in ovarian cancer, the findings may lead to the use of CXCR4 inhibitors as a therapeutic target...
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Scientific poster: Developing protein: Protein Interaction (PPI) assays with AlphaLISA and LANCE TR-FRET
In this scientific poster, PerkinElmer demonstrates the ease and utility of using AlphaLISA® and LANCE® TR-FRET homogenous assay forms for studying PPIs.
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Application note: Performing NanoBRET with the Varioskan LUX multimode reader
In this paper, Thermo Fisher Scientific aim to assess the performance of Thermo Scientific Varioskan LUX when running NanoBRET.
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Charles River announces success of integrated discovery project with ENYO Pharma
Capture compound mass spectrometry technology enables target identification...
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Charles River announces expansion of in vitro oncology services
Partnership with InSphero provides additional 3D solutions...
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Cell surface protein may offer target in treating childhood cancers
Immunotherapy drug candidate could be potent weapon against neuroblastoma and other paediatric malignancies...
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How receptors for medicines work inside cells
G protein-coupled receptors are the key target of a large number of drugs, scientists have now been able to show more precisely how these receptors act in the cell interior...
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PerkinElmer launches new IVIS® Lumina™ S5 and Lumina X5 systems for high throughput in vivo imaging
Advanced 2D imaging and analysis help scientists rapidly trace anatomical and molecular aspects of diseases to advance drug discovery...
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New technique speeds up chemical screening
Researchers have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds...
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Researchers identify powerful pain reliever
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
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Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
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Avenue discovered for precision cancer treatment
A novel chemical dubbed "T-REX," along with a patent-pending targeting molecule have uncovered interesting facets of several well-known cancer-cell mutations that, if present in a patient, could inform treatment options and potentially produce more favourable outcomes...