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A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
Researchers have described a key cellular receptor in the processes of metastasis in ovarian cancer, the findings may lead to the use of CXCR4 inhibitors as a therapeutic target...
In this scientific poster, PerkinElmer demonstrates the ease and utility of using AlphaLISA® and LANCE® TR-FRET homogenous assay forms for studying PPIs.
In this paper, Thermo Fisher Scientific aim to assess the performance of Thermo Scientific Varioskan LUX when running NanoBRET.
Capture compound mass spectrometry technology enables target identification...
Partnership with InSphero provides additional 3D solutions...
Immunotherapy drug candidate could be potent weapon against neuroblastoma and other paediatric malignancies...
G protein-coupled receptors are the key target of a large number of drugs, scientists have now been able to show more precisely how these receptors act in the cell interior...
Advanced 2D imaging and analysis help scientists rapidly trace anatomical and molecular aspects of diseases to advance drug discovery...
Researchers have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds...
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
A novel chemical dubbed "T-REX," along with a patent-pending targeting molecule have uncovered interesting facets of several well-known cancer-cell mutations that, if present in a patient, could inform treatment options and potentially produce more favourable outcomes...
Researchers have used CRISPR-Cas9 to target retinal angiogenesis via an adeno-associated virus to deliver genomic edits to target vascular endothelial cell growth factor...
Paul Grant from Venomtech suggests that because animal venoms contain proteins and peptides that disrupt cell membrane integrity, they offer a new approach to drug discovery...
