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Transplanted brain organoids show response to visual stimuli in adult rats
Researchers say that by looking at individual neurons, they were able to gain a deeper understanding of the integration of transplanted brain organoids.
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Hypothalamus versus hippocampus: changes in the synaptic plasticity
Japanese scientists analyse the associative synaptic plasticity in the supramammillary nucleus–dentate gyrus pathways.
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Combination of MRI and MSI uncover molecular secrets of Alzheimer’s
US researchers will use a unique combination of imaging techniques (MRI and MSI) to study Alzheimer’s disease on a scale that has never been done before.
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New treatment for MS using artificial nerve fibres
Danish researchers undertake a new project that aims to find new forms of treatment for diseases such as MS, which breaks down myelin and nerve fibres, by developing new, artificial nerve fibres
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50 year old blood pressure drug offers alternative treatment for PTSD
US scientists offer a new purpose for the blood pressure drug clonidine as a treatment to reduce the affects of PTSD.
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Deteriorating neurons: the source of human brain inflammation in Alzheimer’s disease
US researchers administered a therapy to Alzheimer’s patient-derived neurons in the lab, eliminating deteriorating cells, leading to positive consequences for the remaining healthy cells.
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How ageing triggers Huntington’s disease
A new study found that as patients age, Huntington’s disease gradually impairs the important cellular housekeeping process autophagy, which is responsible for eliminating waste from cells.
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How neurons stimulate the brain’s microglia
A new MIT study highlights ailing neurons may activate an inflammatory response from the brain’s microglia immune cells.
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Stem cell study reveals how neurons from PTSD patients react to stress
The findings provide insight into how genetics can make someone more susceptible to developing PTSD following trauma exposure.
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Targeting tau – chasing a treatment for Alzheimer’s
Alzheimer’s disease remains one of the largest challenges for the global ageing population. In this article, Victoria Rees, Editor of Drug Target Review, reviews some of the latest research, highlighting how progress has been made in understanding tau as well as how to potentially target this protein as a therapeutic strategy against…
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3D imaging helps to better understand the early stages of Alzheimer’s disease
Researchers have successfully characterised a part of the brain that shows the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease.
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Study reveals how tau impairs communication between neurons in Alzheimer’s
A new study has shown how tau weakens transmission across synapses in the brains of mice, providing insight into Alzheimer's.
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Stem cells could repair spinal cord injuries
Researchers have identified latent stem cells that could respond to spinal cord injuries.
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Scientists capture first images of an autoantibody attacking a neuron receptor
Researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.
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Using cortical spheroids to study endocannabinoids and autism spectrum disorder
The endocannabinoid system may play a role in the development of autism spectrum disorder and might be key to treating people with severe forms of the condition. In this commentary, Dr Karen Litwa, Assistant Professor at East Carolina University’s Brody School of Medicine, US explores how a bioelectronic assay is…