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Evaluating the anti-obesity effects of tocotrienols
The new study found T3s treatment exhibited neuroprotective effects in HFSD-fed mice by mitigating oxidative stress.
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Neuroprotective compounds
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Bodybuilding supplement may help delay Alzheimer’s
US researchers uncover that body building supplement: HMB, may help stop the progression of Alzheimer’s disease.
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Mitochondria repair in mice may provide answers on Parkinson’s disease
Researchers used an experimental small molecule that helped restore the removal of damaged mitochondria from brain cells in a mouse model of Parkinson's.
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Farnesol shows potential to prevent and treat Parkinson’s disease
Researchers have added to evidence that farnesol prevents and reverses brain damage linked to Parkinson’s disease in mouse models.
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Researchers develop new potential stroke treatment
A team has shown that synthetic molecule LAU-0901 plus aspirin-triggered NPD1 can repair brain damage in an experimental model of stroke.
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Researchers use somatostatin to treat Alzheimer’s in mice
A team fused the peptide somatostatin to a brain transport protein and found it treated memory loss associated with Alzheimer's in mice.
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Novel anti-inflammatory slows progression of MS in mice
When delivered intranasally, the anti-inflammatory drug VX-765 prevented axon demyelination and loss in a murine model of multiple sclerosis (MS).
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New class of inhibitors protect mice from neurodegeneration
So called "interface inhibitors" could be used to protect against neurodegeneration, researchers have said.
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Drug could prevent cognitive decline associated with brain tumour radiation
Researchers demonstrated NSPP completely prevented cognitive decline in mice treated with radiation for patient-derived glioblastomas.
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Ursolic acid, compound in fruit peels, reverses damage in murine model of MS
Ursolic acid was shown to halt the progression of chronic multiple sclerosis (MS) and reverse the damage already caused in a mouse model of the disease.
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ZT-1a compound could be an alternative to surgery for brain swelling
Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
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Screening platform reveals compounds that protect neuronal mitochondria
Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
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Powerful molecules provide new findings about Huntington’s disease
Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...
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Scientists uncover the role of PRMT5 in the production of myelin-forming cells
The discovery is a major step toward understanding the mechanisms of myelin production and the potential for treating certain central nervous system diseases...
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Stem-cell technology enables creation of neurons to study brain responses of the super obese
Researchers in the U.S. have tested a technology termed ‘disease in a dish’ that uses stem-cell technology to re-create brain neurons of super obese individuals. The goal is to better understand obesity and potentially enable tailored treatments.