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Scientists develop nanoparticles that can cross the blood-brain barrier
Tested using a new brain tissue model, researchers have developed nanoparticles which may be able to deliver chemotherapy drugs for glioblastoma.
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Mouse study shows gene therapy could fight against rare disease
A new study shows that gene therapy could correct a rare creatine deficiency disorder that commonly results in intellectual disabilities, problems with speech, involuntary movements, and recurrent seizures.
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Ultra-powerful brain scanners offer hope for treating cognitive symptoms in Parkinson’s disease
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
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Animal study shows abnormal activity of brain circuit causes anorexia
Researchers have found that genetically and pharmacologically restoring the normal activity of the brain circuit improved anorexia, opening the possibility of developing a treatment strategy for affected individuals in the future.
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Drug repurposed to boost functional recovery after a stroke
A drug currently prescribed to control seizures and reduce nerve pain may enhance recovery of movement after a stroke.
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Stem cell replacement therapy: a potential treatment for Parkinson’s disease
In a new study, researchers describe a process for converting non-neuronal cells into functioning neurons able to restore capacities undermined by Parkinson’s destruction of dopaminergic cells.
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Researchers use brain organoids to identify neural abnormalities and test gene therapy tools
Scientists used human brain organoids to reveal how a genetic mutation associated with a profound form of autism disrupts neural development, and gene therapy tools to recover the gene’s function effectively rescued neural structure and function.
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Brain organoids may boost drug screening for neurological disorders
Neuroscientists have designed brain organoids to contain both mature neurons and astrocytic glial cells in relative proportions like the human brain.
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Newborn brain cells provide a possible treatment for epilepsy
Scientists gained new insights into how immature astroglia might contribute to epilepsy, opening research towards developing new anti-seizure medications.
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Drug Target Review Vaccine Development ebook 2022
In this ebook, find articles on vaccination strategies for neurodegenerative diseases and the benefits of mRNA vaccine platforms against latent viruses.
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Innovative treatments: the new frontier for mental health
In this exclusive piece, Adrien Châtillon, Co-Founder and CEO of Actipulse Neuroscience, explores the future of treatment for diseases that impact mental health.
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Promising new research could advance memory disorder drug development
Researchers have discovered two types of cells in the brain that are involved in organising discrete memories based on when they occurred. This finding improves the understanding of how the human brain forms memories and could have implications in memory disorders such as Alzheimer’s disease.
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Scientists have shown ageing process can be safely and effectively reversed in mice
New research by the Salk Institute has shown cellular rejuvenation therapy safely reverses signs of ageing in mice.
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Molecular pathway shared by two neurodegenerative disorders found
Scientists have gained deeper knowledge about the mislocalisation of a protein, providing a possible therapeutic target that could have implications in treating dementia.
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New research points to a possible driver of Parkinson’s disease
A study has shown how Parkinson’s disease may be driven by cell stress-related biochemical events that disrupt a key cellular clean-up system.