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Nanotechnology platform could improve stem cell transplantation
A team has developed a technique for identifying pluripotent stem cells that could help research on transplantation medicine.
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Neurosciences
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Motor neuron disease electrical signalling pathways mapped
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
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Encouraging drug discovery and therapeutic targets for dementia
A review has been published by experts in neurodegeneration research, detailing six ways to improve dementia research. This article investigates one of these suggestions, focusing on how we can improve drug target identification.
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Tauopathy-regulating protein identified
Researchers have discovered that the VPS35 molecule can be utilised in preventing neurodegenerative disorders.
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First patient enrolled in Parkinson’s treatment study
A trial has begun in the US for the ENT-01 therapy treatment of Parkinson’s, with the first patient enrolled.
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Betaine supplement reduces schizophrenic behaviours in mice
A new study found that betaine supplementations given to mice reduced schizophrenic behaviours, indicating a drug target.
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Neurodegeneration enzyme identified in mouse models
A new study has found an enzyme in the brains of mice models which induces Parkinson’s, suggesting future drug target.
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Alzheimer’s protein found, suggesting new drug target
Researchers have found a new drug target for Alzheimer’s disease after identifying a facilitating protein.
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Improved human brain organoids to aid neurological disease research
Researchers have grown identical brain organoids for the first time, opening avenues for neurological research.
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New drug target for depression identified
Researchers find key molecule in depression and identify new therapeutic targets.
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Zebrafish reveal insights into Parkinson’s
The findings offer clues that could one day lead to treatments for the neurological condition...
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New technology to produce dorsal cortical neurons using iPS
Scientists expect that it will soon be possible to treat brain diseases by restoring damaged areas in the brain by mass producing neurons using stem cells...
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Neurofilament light chains detect Alzheimer’s damage before symptoms
A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease...
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Nuclear tracers help assess new drugs for neurodegenerative diseases
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
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Application note: GABAA Receptors
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
