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Neurosciences

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Alzheimer’s protein found, suggesting new drug target

13 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have found a new drug target for Alzheimer’s disease after identifying a facilitating protein.

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Improved human brain organoids to aid neurological disease research

7 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have grown identical brain organoids for the first time, opening avenues for neurological research.

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New drug target for depression identified

23 May 2019 | By Victoria Rees (Drug Target Review)

Researchers find key molecule in depression and identify new therapeutic targets.

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Zebrafish reveal insights into Parkinson’s

9 April 2019 | By Drug Target Review

The findings offer clues that could one day lead to treatments for the neurological condition...

news

New technology to produce dorsal cortical neurons using iPS

1 April 2019 | By Drug Target Review

Scientists expect that it will soon be possible to treat brain diseases by restoring damaged areas in the brain by mass producing neurons using stem cells...

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Neurofilament light chains detect Alzheimer’s damage before symptoms

22 January 2019 | By Drug Target Review

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease...

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Nuclear tracers help assess new drugs for neurodegenerative diseases

21 January 2019 | By Dr Zara Kassam (Drug Target Review)

New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.

whitepaper

Application note: GABA_A Receptors

11 December 2018 | By SB Drug Discovery

SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.

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Compounds in coffee may fight Parkinson’s

11 December 2018 | By Drug Target Review

Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration...

news

Depleting ErbB4 gene alleviates Schizophrenia symptoms in new mouse models

3 December 2018 | By Dr Zara Kassam (Drug Target Review)

Restoring brain cell receptors helps restore normal behaviour...

news

MRI scans shows promise in predicting dementia

23 November 2018 | By Drug Target Review

Brain changes evident in scans before memory, cognitive decline...

news

New information on the pathological mechanisms of Alzheimer’s disease

21 November 2018 | By Drug Target Review

Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...

Charles River Laboratories Continues Commitment to Oncology Drug Discovery

news

Charles River Laboratories continues commitment to oncology drug discovery

16 November 2018 | By Charles River Laboratories

Team of oncology experts expand data in Tumor Model Compendium and present strong portfolio at industry conferences...

news

Sensory neurons can be used to discover therapies for ALS

9 November 2018 | By Drug Target Review

New approach for testing for ALS may be useful to reverse debilitating disease...

news

Brain activity pattern may be early sign of schizophrenia

8 November 2018 | By Drug Target Review

In a study that might enable earlier diagnosis, neuroscientists find abnormal brain connections that can predict the onset of psychotic episodes...

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Neurosciences