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Neurosciences

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Link between TB and Parkinson’s disease identified

23 May 2018 | By Dr Zara Kassam (Drug Target Review)

The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...

news

Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation

18 May 2018 | By Charles River Laboratories

Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.

news

SB216763 shows preclinical efficacy in Rett syndrome

16 May 2018 | By Drug Target Review

Researchers describe how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome...

news

Targeting cPLA2 may improve the treatment of epilepsy

10 May 2018 | By Drug Target Review

New findings demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy...

news

Cambinol halts spread of toxic protein associated with Alzheimer’s progression

8 May 2018 | By Dr Zara Kassam (Drug Target Review)

Research could help lead to the design of drugs that slow neurodegeneration...

news

Therapeutic RNA corrects splicing defect that causes familial dysautonomia

2 May 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...

news

Lipid accumulation in the brain may be an early sign of Parkinson’s disease

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...

webinar

in vitro phenotypic assays for Parkinson’s disease

26 April 2018 | By Charles River Laboratories

This webinar highlights cell based assays for Parkinson’s disease that include endpoints such as a-synuclein aggregation and mitophagy readouts.

news

Stem-cell technology enables creation of neurons to study brain responses of the super obese

23 April 2018 | By Drug Target Review

Researchers in the U.S. have tested a technology termed ‘disease in a dish’ that uses stem-cell technology to re-create brain neurons of super obese individuals. The goal is to better understand obesity and potentially enable tailored treatments.

news

Scientists discover hidden structure of enigmatic ‘backwards’ neural connections

17 April 2018 | By Drug Target Review

Scientists reveal the existence of dense connections in the brain...

news

Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis

11 April 2018 | By Dr Zara Kassam (Drug Target Review)

Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...

news

BNIP1 identified as a risk gene for ALS

10 April 2018 | By Dr Zara Kassam (Drug Target Review)

Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...

news

An advance for precision medicine

10 April 2018 | By Drug Target Review

Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...

news

New method allows scientists to watch brain cells interacting in real time

6 April 2018 | By Drug Target Review

Findings could deepen understanding of neurological disorders...

news

Ultrathin endoscope captures neurons firing deep in the brain

28 March 2018 | By Dr Zara Kassam (Drug Target Review)

A new fibre-based endoscope, tested in mice, poised to bring new insights into brain function...

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Neurosciences