news
fMRI-neurofeedback shows promise in treating tinnitus
By using functional MRI researchers have found that neurofeedback training has the potential to reduce the severity of tinnitus or even eliminate it...
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Neurosciences
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Study reveals new mechanisms of cell death in neurodegenerative disorders
Researchers have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders...
news
Charles River Laboratories presents newly expanded capabilities at Neuroscience 2017
Charles River Laboratories International, Inc. announced that its team of neuroscience drug discovery experts is presenting 27 scientific posters, both independently and collaboratively with clients, at Neuroscience 2017, the 47th annual meeting of the Society for Neuroscience (SfN).
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Metabolic collaboration linked to Alzheimer’s disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
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Parkinson’s UK Drug Discovery Manager joins DTR advisory board
Drug Target Review welcomes Janusz Kulagowski to its advisory board ...
article
Flow cytometry – accelerating neuroscience research
Flow cytometry continues to evolve at a fast pace and provides neuroscientists with the ability to perform many highly-specialised assays simultaneously. It meets the demands of cutting-edge research in neuroscience that has allowed researchers to isolate particular neural cells from heterogeneous population and catalogue its molecular or physical features...
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Researchers identify powerful pain reliever
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
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Metrion extends collaboration with LifeArc
Metrion Biosciences Limited and LifeArc, today announced an extension of their existing partnership...
news
Plasma membrane protein may generate new neurons in the hippocampus
New research in suggests that the protein Efr3a regulates the BDNF-TrkB signaling pathway, which plays an important role in regulating learning and memory...
article
A new approach to Organ-on-a-Chip
Draper's Joe Charest explains how synthetic organoids can lead to safer drug testing, and why organ-on-a-chip technology is the future of drug discovery...
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Stem cell patch shows early promise in treating heart failure
In a Phase I clinical trial, heart failure patients treated with patches made from their muscle cells showed improved exercise capacity and heart function after one year. Stem cell patch-based therapy may be a viable heart failure therapy and should be validated in larger clinical trials, researchers conclude.
webinar
Assessing neurological ion channel therapeutic and liability targets
10 March 2017 | By Charles River
This webinar explores neurological ion channel therapeutic and liability targets, featuring four subtypes of NMDA receptors. We also discuss the rationale and options for assessment of therapeutic compounds on panels of CNS ion channels for evaluating their risk for CNS liabilities...
news
Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
news
Brain-machine interfaces: bidirectional communication at last
Since the early seventies, scientists have been developing brain-machine interfaces; the main application being the use of neural prosthesis in paralyzed patients or amputees. A prosthetic limb directly controlled by brain activity can partially recover the lost motor function. This is achieved by decoding neuronal activity recorded with electrodes and…
webinar
Fine Motor Kinematics in In Vivo Pharmacology
1 December 2016 | By Charles River
This webinar details a novel automated and high-precision system to successfully analyze early changes in muscular or neuronal function in disease models...