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Neurosciences

Improving Huntington’s disease drug discovery with new reproducible disease models

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Huntington’s disease: danger of repeated DNA sequences

9 November 2023 | By Drug Target Review

Scientists find a way to slow the progression of Huntington’s disease by analysing DNA and find the basis of a potential treatment.

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Utilising CAAR T cells to treat antibody-caused brain disease

6 November 2023 | By Drug Target Review

Researchers have engineered CAAR T cells to destroy harmful antibodies, improving NMDA receptor encephalitis treatment.

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Reduced motor symptoms of Parkinson’s disease

3 November 2023 | By Drug Target Review

In rodent and nonhuman primate animals, circuit-specific gene therapy offers promise for Parkinson’s disease and other brain disorders.

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Metabolic change in hippocampus indicates Alzheimer’s disease

1 November 2023 | By Drug Target Review

Using RNA sequencing, scientists find that metabolic increase in the brain is an early indicator of Alzheimer's disease.

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Huntington’s disease: a way to prevent cognitive decline

19 October 2023 | By Drug Target Review

Discovery about Huntington’s disease may apply to other neurodegenerative disorders, like Alzheimer’s and frontotemporal dementia.

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New material engineered can repair severed nerves

18 October 2023 | By Drug Target Review

Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.

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AI: age prediction model on human brain tissue developed

12 October 2023 | By Drug Target Review

For the first time ever, researchers have developed an algorithm to predict age at death and indicate early changes related to disease.

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Drug Target Review Neuroscience eBook 2023

5 October 2023 | By Drug Target Review

Explore cutting-edge neuroscience insights through an exclusive interview with Dr Olga Chechneva on nuclear interactions in the mouse brain and a groundbreaking study by MIT researchers revealing key aspects of Alzheimer's disease. Download your FREE eBook!

Computer recreation of dopaminergic neurons (involved in Parkinson's) in blue and pink

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New cell discovery shakes up neuroscience

12 September 2023 | By Drug Target Review

Scientists have identified a novel cell type that combines astrocytic characteristics with the machinery for synaptic transmission. This discovery resolves years of debate in the field.

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MSK1’s importance for cognitive benefits

28 July 2023 | By Izzy Wood (Drug Target Review)

New study uncovers role of a neuronal protein kinase called mitogen- and stress-activated protein kinase 1 (MSK1) in mediating the cognitive benefits of environmental enrichment.

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Newly discovered mechanism behind cognitive decline in aging

27 July 2023 | By Izzy Wood (Drug Target Review)

US researchers say new mechanism could lead to new drugs and therapies to treat normal cognitive decline in aging.

Sport,,Fitness,,Healthy,Lifestyle,And,People,Concept,-,Close,

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Bodybuilding supplement may help delay Alzheimer’s

25 July 2023 | By Izzy Wood (Drug Target Review)

US researchers uncover that body building supplement: HMB, may help stop the progression of Alzheimer’s disease.

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New guidelines for diagnosing Alzheimer’s disease

17 July 2023 | By Izzy Wood (Drug Target Review)

Guidelines unveiled at AAIC 2023 using blood biomarkers offer faster and more effective Alzheimer's diagnosis.

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Substance abuse inhibits cognitive flexibility

13 July 2023 | By Izzy Wood (Drug Target Review)

New US research underlines the relationship between substance use and significant modifications to an inhibitory brain circuit, resulting in decreased cognitive flexibility

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New biomarker identified for major depressive disorder

6 July 2023 | By Izzy Wood (Drug Target Review)

Local gyrification index, which measures cortical folding in the brain, could be a novel neuroimaging marker for major depressive disorder.

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Neurosciences