Targeted cancer vaccines eliminate tumours and prevent recurrence in mice
Researchers have developed an mRNA-based cancer vaccine that is delivered directly into the lymphatic system for a more potent response.
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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
Researchers have developed an mRNA-based cancer vaccine that is delivered directly into the lymphatic system for a more potent response.
The researchers identified key molecular differences between triple-negative breast cancer cells that cling to an initial tumour and those that venture off to form distant tumours.
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
New study has demonstrated that mice deficient in dendritic cell immunoreceptor are resilient against colitis and colonic tumour growth.
A T-cell bispecific antibody shows potent anti-tumour activity in preclinical models of epidermal growth factor receptor variant III (EGFRvIII) mutant glioblastoma.
Researchers analysed the expression of long non-coding RNAs in samples from patients and tumour cell lines, identifying a group of genes with augmented expression in pancreatic cancer.
F-star Therapeutics has announced a licence agreement with Takeda for a novel next-generation immuno-oncology bispecific antibody.
The scientists say that shutting down the EBAG9 gene allows the body to destroy tumour cells earlier and more radically.
Researchers have identified an important gene that could enable more targeted treatment for cancer.
Researchers from the US have identified several new small molecules that can induce mitophagy in leukaemia cells.
A recent whole genome sequencing study has revealed hidden insights into the causes of cancer. In an exclusive article, Dr Andrea Degasperi from the Early Cancer Institute at the University of Cambridge, UK spoke to Drug Target Review's Ria Kakkad about the study's implications and the future of whole genome sequencing.
A new study has shown that it is possible to reverse key process that allows pancreatic cancer cells to grow and spread around the body.
For the first time, researchers have tested a molecule that combines three distinct technologies against glioblastoma, the most aggressive type of brain cancer.
When the researchers increased the mitochondrial content with an inhibitor, the cancer cells responded to the treatment.
New research has shown that using viral and bacterial vaccine approaches together is safe and far more effective at fighting the cancer than either approach by itself.