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Preventing tumour growth
Researchers have developed a novel substance that disables a protein in the cell skeleton, leading to cell death. In this way, substances of this type can prevent the growth of tumours.
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Simple delivery method that enhances a promising cancer treatment
Scientists have developed a delivery method that enhances treatment by adding CAR T cells and specialising signalling proteins to a hydrogel that is injected next to a tumour.
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Innovative therapy that “tricks” and destroys cancer cells
New research has shown iron-like compound holds promise for treating patients with glioblastoma, an aggressive brain cancer.
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How to develop the next generation of CAR T-cell therapies
CAR T cells have shown incredible promise in the clinic, but there is still room for advancement. One avenue for improvement is through modification of the CAR design. However, given the number of exchangeable domains, testing all variations can present a hurdle. In this article, Dr Sarwish Rafiq, Assistant Professor in…
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Mystery behind odd-shaped blood cancer cells revealed
Researchers have found that the Lamin B1 mutation causes odd-shaped nuclei in blood cancer cells, which may lead to improved care for leukaemia patients.
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Researchers create triple-negative breast cancer organoids
Scientists have opened a path towards triple-negative breast cancer treatment, by creating organoids from tumour samples.
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How RNA molecules can control repair of human DNA in cancer cells revealed
New research from the Karolinska Institutet shows that RNA molecules have a much broader function in the development of cancer.
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New pre-clinical study demonstrates innovative approach to treating brain diseases
Researchers have been able to slow down the progression of glioblastoma in mice, the most common adult brain cancer.
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Avacta selects chemotherapy drug candidate for pre-clinical development
Avacta Group announced that the chemotherapy candidate AVA3996 will be developed with a view to a first-in-human clinical trial beginning in 2023.
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Opportune identification of novel multiple myeloma target
During investigations into the tropical disease Buruli ulcer, researchers have instead identified a promising new avenue for potential treatments for multiple myeloma.
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Novel method for chemo capture – up to three times more effective
A team of researchers in the US has devised a new means of removing excess chemotherapy drugs from a patient’s bloodstream, with potential for wider clinical and materials science applications.
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Treating cancer patients with cancer anorexia-cachexia syndrome
In this article, Patrick Kendall, Scientific Advisor for Artelo Biosciences, outlines why future treatment of cancer anorexia-cachexia syndrome may lie with drugs in development offering a mechanistic approach.
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T-cell immunotherapies and flow cytometry
Dr Alasdair Gunn and Natalie Bath from Adaptimmune explain how flow cytometry provides a useful tool for the development of immuno-oncology therapies. They also explore how they use this method for translational research of the company’s SPEAR T-cell products.
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Nanotechnology boosts immune response at tumour site in mice
The new nanotechnology left six of 10 mice with lymphoma tumour-free and was effective in melanoma when combined with existing drugs.
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Researchers investigate gene network to identify “cancer driver genes”
The new study looked at the network of gene-gene interactions associated with cancer onset and progression to identify therapeutic targets.
