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Transfer of oncogene in colon cancer cells demonstrated
A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Study identifies protein key to successful chemotherapy
A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
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Gene discovered to play key role in cancer metastasis
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
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Inhibiting protein slows glioblastoma tumour growth
Researchers have discovered that inhibiting the ID1 protein slows the growth of glioblastoma tumours and reduces resistance to chemotherapy.
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Discovering new routes to cancer drug discovery with neutrons
From the world’s flagship neutron science facility, Institut Laue-Langevin (ILL), Matthew Blakeley shares insights into how they are harnessing the power of neutrons to aid their search for new cancer treatments.
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Common cold strain found to kill bladder cancer cells
New research has found a strain of the common cold that can attack cancer cells in the bladder resulting in cell death with no side effects.
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Study identifies protein pathway key in cancer growth
Researchers have discovered a pathway which when blocked can cause cancer cell death, pointing to new therapies.
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Regulatory skin cancer protein identified
A new study has discovered the role of a protein in controlling the development of skin pigment genes.
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Study reveals antioxidant role in spread of lung cancer
Researchers have discovered that lung cancer cells metastasise using antioxidants, informing potential future therapies.
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Job cuts limit cardiovascular and diabetes research and development
Pharmaceutical company, Sanofi, will eliminate jobs in France and Germany and end new in-house cardiology research programmes.
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Biomarkers for potential cancer immunotherapy identified
Researchers have found two biomarkers which play a significant role in the invasion of tumours by T-cells.
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Image-based characterisation of cancer biotherapeutics
Scientists from LifeArc, an independent medical research charity in the UK, explain how they’re using the latest imaging technologies to progress drug discovery campaigns and identify the most promising candidates for antibody-based therapies.
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Stem Cell In-Depth Focus 2019
This in-depth focus looks at the modification of stem cells to facilitate their efficient delivery to tumours, highlighting the new development of pluripotent stem cells.
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Drug Target Review – Issue 2 2019
In this issue: novel approaches to produce radiolabelled antibodies, the use of CRISPR/Cas9 to accelerate the development of targeted therapies and utilisation of stem cells to study the effects of cannabis on neuronal development.
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Method for radiolabelling antibodies against breast cancer developed
Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light - with proteins being ready-to-use for cancer imaging or therapy in less than 15 minutes.
