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New study finally explains the link between inflammation and gastric cancer
Researchers have finally shown how inflammation caused by H. pylori infection causes the proliferation of gastric epithelial stem cells, leading to gastric tumours.
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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New cancer drug targets accelerate path to precision medicine
Researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival...
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Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours
Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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HER2-targeted CAR T-cell therapy shows promise in patients with sarcoma
A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in paediatric and adult patients with advanced HER2-positive sarcoma...
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The key to greater efficacy in cancer treatment?
Mitochondria are found to be associated with the effectiveness of oncological drug therapies...
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USP15 enzyme could have role in the future treatment of cancer
Researchers have found that the enzyme USP15 could potentially lead to new therapies for both breast and pancreatic cancer...
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Optical imaging technique to detect tiny tumours
A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
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Potential EBV-associated cancer treatment in small molecule inhibitors
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
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Genomics to match treatments to pancreatic cancer patients
Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
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Protein marker in response to brain cancer therapy
An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
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Colon cancer pathway discovery could lead to targeted therapies
Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer...
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Counteracting T-cell exhaustion in CAR-T cancer therapies
Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
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Microfluidics device to detect cancer cells in blood
A recently developed microfluidics device is able to detect and separate out cancer cells in blood, without the need for dilution...
