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T-cells engineered to recognise tumours expressing the CD30 protein marker
Researchers have genetically engineered immune cells to recognise and fight Hodgkin and non-Hodgkin lymphoma cells...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Genes linked to dementia identified
Nanoscientists have identified genes that link to dementia, in the hope that future therapies could target these genes for positive results in patients...
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High-throughput platform could map cancer drug target activity
Manchester University researchers have developed a high-throughput platform to analyse and study a family of enzymes that are linked to cancer...
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Application note: A complete next-generation sequencing workflow for circulating cell-free DNA isolation and analysis
Circulating cell-free DNA (cfDNA) has been shown to have potential as a noninvasive substrate for the detection and monitoring of tumour cells. As circulating tumour DNA is often present at low frequencies within cfDNA, targeted sequencing is an optimal tool for mutation detection.
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Starving lung cancer could be an effective treatment
A recently discovered enzyme could lead to the development of a treatment where cancer cells are starved of 'food' provided by this protein...
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Customer testimonial PHERAstar FSX and CLARIOstar
Laura Kilpatrick, Chloe Peach and Carl White from the University of Nottingham talk about cancer research and how they use our microplate readers PHERAstar and CLARIOstar.
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Halting the spread of brain cancer
Mouse models used to show how convection enhanced delivery caused glioma cells to invade the rest of the brain could help to prevent this spread in future...
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War On Cancer 2018: targeted therapies in oncology
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
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New technique to simultaneously target fibroblasts while killing cancer cells
Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells...
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Charles River Laboratories continues commitment to oncology drug discovery
Team of oncology experts expand data in Tumor Model Compendium and present strong portfolio at industry conferences...
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RIP1 kinase as a therapeutic target for pancreatic cancer
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
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Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
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Making old antibiotics work better using r8
A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...
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Paclitaxel acting as an immune response modulator
Brazilian researchers have discovered that a drug widely used as for chemotherapy also acts as an immune response modulator...
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Cyclic peptoids show promise as prostate cancer drug
Scientists in the U.S. have developed molecules, termed cyclic peptoids, that block the action of genes that drive the growth of therapy-resistant prostate cancer, according to a new study.
