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‘Paintable’ chemotherapy for melanoma shrinks tumours
A hydrogel incorporating transfersomes and chemotherapy drugs incorporated with some intravenous medication may be the best treatment for melanoma...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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CT45 biomarker found in ovarian cancer can predict response to therapy
New approach could prolong survival and trigger an immune...
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Expert view: Creating metabolic liabilities to target cancer
As the pace of genetic approaches to combating cancer slows, researchers are focusing on novel approaches to identify and create metabolic liabilities in cells. Cancer cells rewire their metabolism to survive and proliferate rapidly; however, there is no single metabolic phenotype that enables this rewired state.
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New drug Metavert blocks growth of pancreatic cancer in mice
Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.
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Breast tissue simulations address enhanced MRI delays
Researchers address the delay of enhanced MRI cancer detection using simulations of women's breast tissue and higher MRI strengths...
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Nanotherapy offers hope in treating drug-resistant renal cell carcinoma
A research team has developed a nano-platform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma...
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Cancer cells hide to evade immunotherapy
Cancer cells have been found to evade immunotherapy by hiding behind human leukocyte antigens, with researchers identifying therapies to prevent relapse...
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Np63a should be targeted in squamous cell carcinomas
A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...
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Nuclear PET imaging method developed for tumour detection
Researchers have developed a PET imaging method suitable for many forms of cancer, with high contrast and less inconvenience to patients...
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Expert view: Managing the complexity of finding new targets and drugging the undruggable
Assessing targets that are unable – or rather, extremely difficult – to reach pharmacologically, has prevented researchers from achieving desired clinical successes, most notably in the realm of cancer research. However, many advances are being made to shedlight on these difficult yet desirable target areas.
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Expert view: New developments in real‑time live‑cell analysis
Live-cell analysis is now a well-established method that is part of the everyday cell biologist’s armoury for understanding cell biology. For over a decade, the functionality, throughput, and ease of use offered by real-time live-cell analysis has provided a platform for accurate and reproducible cell biology analysis in multiple biomedical…
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Antibody-based approach to destroy deadly ovarian cancer
Researchers are developing an antibody-based approach to destroy deadly ovarian cancer -- an approach that could also be modified to kill breast, prostate and other solid tumours...
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Discovery of markers that predict evolution of triple-negative breast cancer
Researchers in Spain have identified a means of classifying patients with the most aggressive form of breast cancer - triple negative breast cancer; providing meaningful prognosis for the first time.
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NanoMIPs efficiently target and eliminate cancer cells
A joint research team has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs...
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Experimental drug targets cancers associated with Epstein-Barr virus
An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...
