Macrophages support mammary stem cells via chemical signalling
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
Researchers are reporting an innovative new method to screen for potential cancer drugs...
A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells...
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.
A CAR-T-based immunotherapy successfully kills tumours and prevents metastatic growth, in final preclinical tests before human trials...
Scientists have investigated the mechanisms by which the lymphatic endothelial cells modulate metastasis in melanoma, providing new targets for therapy development.
This article focuses on how the immune system functions, the challenges that it presents to drug development and why there are such concerns around safety that need to be investigated in pre-clinical studies. Moreover, it covers the role of checkpoint inhibitors as an attractive target for cancer immunotherapy.
Scientists use data from human cancers and C. elegans to understand mutational causes of cancer...
27 April 2018 | By Mitra Biotech
In this webinar, speaker Mark Paris, PhD discussed a recent study evaluating a cohort of HNSCC patient tumours treated with anti-PD1 using CANscript TM;. He also be reviewed the results of this study as a means of investigating predictors of clinical response and identifying mechanisms of resistance.
Obesity could enhance cancer development while aspirin might prevent it - a new insight into potential targets for cancer prevention.
Combination therapy co-targeting the mitochondria enhances the antitumour effect of telomerase inhibition in NRAS-mutant melanoma.
A team of scientists have reported that tumour progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.