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Extracellular vesicles could be personalised drug delivery vehicles
Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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EDC4 gene involved in familial breast cancer
An international research consortium has identified a novel gene involved in breast cancer
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Drug Target Review – Issue #1 2018
In this issue: how customised cell engineering advances immunotherapy, how insights into auto-immunity are providing new opportunities for immune-oncology, and advances in lab automation and robotics are accelerating the pace of antimicrobial therapy.
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
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New treatment for aggressive breast cancer
Researchers have uncovered a way to treat aggressive tumours through manipulation of the connective tissue cells of the tumour.
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Modified PIP protein differentiates between cancerous and non-cancerous cells
A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
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Imaging agent helps predict success of lung cancer therapy
Doctors may soon be able to predict the efficacy of a widely used lung cancer drug based on an imaging agent and a simple scan.
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Splicing-variant detection method identifies biomarkers for HCC
Researchers report a method for identifying splicing-based biomarkers for hepatocellular carcinoma....
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Scientists advocate less toxic treatment for rare leukaemia (MPAL)
Researchers in the US have undertaken meta-analysis studies to ascertain the optimum approach for doctors treating rare mixed phenotype acute leukaemia (MPAL). They found that a less-toxic regimen gives better results.
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Charles River Laboratories announces new tumour model compendium
The Compendium provides scientists an online resource to help design efficient in vitro and in vivo oncology research studies.
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New analytical method provides an insight into additional chromosomes
A new technique promises to identify additional chromosomes involved in carcinogenesis.
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Five genetic changes linked to pancreatic cancer risk
Researchers have discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer...
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Local environment plays key role in breast cancer progression
While studying the complex correlation between tissue stiffness and breast cancer development, researchers found that cancer cells tend to become more aggressive when the surrounding tissue stiffens...
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Flexible warped nanographene developed for bioimaging
An international team of scientists has developed a water-soluble “warped nanographene”, a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging.
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STEEL gene senses inadequate blood flow in microscopic blood vessels
A new study has found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues...
