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Blood-brain-barrier modelled in 3D on precision chip
Researchers have engineered a chip which allows 3D modelling of the blood-brain-barrier and has provided insight into how astrocytes facilitate transport of molecules.
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Organ-on-a-Chip
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Body-on-chip technology: resolving current limitations in drug discovery
Researchers have developed a new body-on-chip technology that can demonstrate the pharmacokinetics and pharmacodynamics of drugs in a pre-clinical setting without the need for animal testing.
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Liver-Chip used to study toxicity of drug candidates
Researchers have made a ‘Liver-Chip’ which is able to demonstrate the toxic effects of drug candidates and compounds in human patients.
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Pancreas-on-a-chip technology to aid in diabetes research
Scientists combine organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research.
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Scientists develop retina-on-a-chip to study eye diseases
Combining organoid and organ-on-a-chip technologies, researchers have created a model which will allow them to study eye diseases and treatments for the retina.
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Researchers discover bronchospasms mechanisms using microdevice
A ‘bronchi-on-a-chip’ has been created by researchers to identify the processes of bronchospasms which could aid in respiratory disease therapies.
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Organ-on-an-electronic-chip could be used in drug development
Researchers have created a new organoid model that can be used to study systems such as the heart and the effects of drugs on these cells.
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Five latest developments for models
The use of models is a key feature of preclinical studies and in recent months there have been several new advancements in this area. This article investigates five of the latest developments.
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Researchers develop biosensor with real-time oxygen monitoring
In a study, researchers have developed a biosensor concept using organs-on-a-chip to measure the levels of oxygen in real-time...
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Expert view: Rising growth of the global high‑content screening software and services market
The global high-content screening (HCS) software and services market accounted for over $500 million in 2017 and is expected to reach approximately $1.4 billion by 2026, increasing at a compound annual growth rate of more than 11%, says Jeff McMillan, Senior Product Manager Imaging, Molecular Devices.
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ELRIG UK hosts inaugural Discovery Technologies event
ELRIG (European Laboratory Research & Innovation Group) has announced its first Discovery Technologies meeting, which will take place at Alderley Park, located near Macclesfield in Cheshire.
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ALS researchers begin recreating human spinal cords on a chip
NIH-funded study closes in on personalised drug testing for neurological disorders...
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Effective drug transfer tests look promising for placenta-on-a-chip technology
Researchers in America have demonstrated the feasibility of their ‘placenta-on-a-chip’ platform in studying how drugs are transported across the human placental barrier.
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Organ-on-chip technology tests for hepatitis B virus
Scientists have become the first in the world to test how pathogens interact with artificial human organs...
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Blood-vessel-on-a-chip provides insight into new anti-inflammatory drug candidate
Researchers have discovered that synthetic APC-mimicking molecules provide anti-inflammatory and anti-thrombotic protection to endothelial cells without interfering with blood clotting...
