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Cilia-free stem cells could open a new way to study rare diseases
A new study has shown that cilia-free human pluripotent stem cells could help scientists understand the causes of polycystic kidney disease and other cilia-linked illnesses.
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Organoids
podcasts
Episode 8 – 3D imaging with Hilary Sherman, Corning Life Sciences & Dr Oksana Sirenko, Molecular Devices
In this episode, experts explore the benefits of 3D imaging and the important considerations for organoid workflows in research and drug development.
news
Nose organoids reveals first stages of SARS-CoV-2 and respiratory syncytial virus infection
Using nose organoids, researchers have highlighted key differences between the infection by SARS-CoV-2 and that of respiratory syncytial virus.
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Brain organoids may boost drug screening for neurological disorders
Neuroscientists have designed brain organoids to contain both mature neurons and astrocytic glial cells in relative proportions like the human brain.
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A three-dimensional model for rare neuromuscular disorders
Scientists have created a tiny, bioengineered 3D model that mimics the biology of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy, a pair of rare, devastating neuromuscular diseases.
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Personalised organoid models for rare spinal cancer
Scientists have successfully created viable organoids from tumour samples from five patients with a rare bone cancer called a chordoma, which has few therapeutic options.
whitepaper
Under the microscope: Unveiling a next-generation imaging system with deep learning technology
The ImageXpress Confocal HT.ai High-Content Imaging System combines premium hardware technology with a self-learning software analysis workflow for increased signal and ultra-fast 3D organoid screening.
whitepaper
Product hub: Scalable and automated 3D cell cultures for high-throughput and high-content screening
Read about hydrogels that provide defined and tuneable material properties that allow the controlled inclusion of biochemical cues.
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Scientists create brain organoids to understand autism
Researchers have been using brain organoids to understand how a mutated gene affects the brain at its very early stage of development.
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Researchers create triple-negative breast cancer organoids
Scientists have opened a path towards triple-negative breast cancer treatment, by creating organoids from tumour samples.
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Study highlights possibility of using 3D organoids of the cervix to test drugs
A new study modelled chlamydia and HPV co-infection in patient-derived ectocervix organoids to reveal distinct cellular reprogramming.
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Breakthrough method developed to grow model organs
Researchers have successfully generated organoids in suspension, offering the possibility of larger-scale experiments to study human development and disease.
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Game-changing model to identify drugs that may slow AMD
Researchers have identified potential age-related macular degeneration drugs using a novel stem-cell based research tool.
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Engineered airway lining created to study how COVID-19 affects respiratory tracts
Researchers have made a respiratory model of COVID-19, made from patient-derived stem cells, to understand how the virus affects respiration and which could be used to test possible drugs.
news
Organoid system simulates human liver-islet axis in diabetes
Scientists have developed a multi-organoid system from stem cells that can replicate the liver-islet axis in type 2 diabetes.
