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Scientists have identified an important new mechanism that causes the heart’s muscle to thicken which markedly increases the risk of irregular heart rhythms and cardiac hypertrophy.
In a new study, researchers have demonstrated the efficiency of T-cell immune response against the Omicron variant of SARS-CoV-2.
Scientists have created a pipeline for identifying, prioritising and evaluating potential tumour antigens for personalised cancer vaccines.
In an exclusive with Drug Target Review, researchers at the University at Buffalo explain how they developed a novel peptide that could be a future treatment for chronic inflammatory pain.
Professor Christian Heinis explains how peptides could offer the next generation of therapeutics and what is required to screen libraries of cyclic peptides.
Scientists have created new nanoparticle-based materials that could be used to deliver gene therapies in an adaptable way.
A synthetically made glycopeptide biologic has shown promise as a treatment for obesity-related diseases in mice.
A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.
A team has demonstrated in mouse models that a self-assembling nanofibre material could limit the damage caused by cytokines in inflammatory diseases.
Although macrocyclic peptides make for promising pharmaceutical candidates, screening for lead peptides has proved difficult for scientists. In a new study, researchers at the Technion-Israel Institute of Technology addressed these challenges by developing a novel high-throughput screening assay for cyclic peptides with affinity to the ubiquitin protein. Drug Target Review’s…
In this ebook, find articles exploring some of the assays used to identify the most promising COVID-19 drugs and discussing the development of a novel assay to reveal potential peptide therapeutics for cancer.
A peptide that could treat multiple sclerosis caused no neurotoxicity or cardiotoxic effects in zebrafish, a study has shown.
A high-throughput screening assay for macrocyclic peptides with affinity to ubiquitin has been created by researchers.
A peptide administered to ferrets protected them from SARS-CoV-2 viral transmission when housed with infected ferrets.
A novel nanotherapy can decrease intestinal inflammation and shrink lesions in rodent models of Crohn's disease, a study has shown.
