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whitepaper

Application note: Effect of perfluorinated alcohols in impurity analysis for synthetic oligonucleotides

7 August 2020 | By Phenomenex

Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.

whitepaper

Application note: Effect of alkylamine based Ion-pairing reagents in analysis of siRNA

7 August 2020 | By Phenomenex

Silencing RNA, or siRNA, are short, double-stranded RNA molecules which are not only an important research tool in molecular biology, but also an emerging therapeutic modality.

Application note Comparison of fully porous and superficially porous particles

whitepaper

Application note: Comparison of fully porous and superficially porous particles for the analysis of synthetic oligonucleotides

7 August 2020 | By Phenomenex

Superficially porous particle technologies provide a reduced diffusion path in comparison with their fully porous counterparts minimising the resistance to mass transfer during chromatographic separation.

webinar

Mobile phase optimisation for oligonucleotide analytical methods by LC-MS

1 July 2020 | By Phenomenex

In this on-demand webinar, we provide an overview of nucleic acid therapeutics and discuss the chromatographic challenges associated with oligonucleotides. We also explore modulation of the mobile phase additives alkylamine ion pair and perfluorinated alcohols. Finally, we will show how optimisation of mobile phase can improve not only chromatographic performance…

webinar

Drug repurposing approaches to fast track development of new therapies for COVID-19

26 June 2020 | By Tecan

This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.

webinar

Improving cell-based assays and their future in drug discovery

15 June 2020 | By Horizon Discovery

Watch our on-demand webinar with Horizon Discovery which summarises the challenges in translating promising pre-clinical therapeutic candidates into clinical success.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

whitepaper

Application note: High-throughput pathogen detection using a novel MagMAX kit and OpenArray technology

9 June 2020 | By Thermo Fisher Scientfic

Automated detection and isolation of pathogens for multiple samples types.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

whitepaper

Application note: Sensitive detection of viral nucleic acids

8 June 2020 | By Thermo Fisher Scientific

A simple and sensitive method for nucleic acid extraction from virus-containing samples, with a range of viral loads.

whitepaper

Application note: Metagenomic analysis of the human microbiome

8 June 2020 | By Thermo Fisher Scientfic

Isolate high-quality, inhibitor-free DNA and RNA from human stool and other sample types suitable for metagenomics sequencing.

webinar

Establishing Alpha CETSA HT in primary screening

7 May 2020 | By PerkinElmer

High-throughput screening (HTS) cascades have evolved to ensure that high quality hits can be identified from large screening collections.

news

Induced pluripotent stem cells and CRISPR reversed diabetes in mice

23 April 2020 | By Victoria Rees (Drug Target Review)

Induced pluripotent stem cells made to produce insulin and CRISPR, used to correct a genetic defect, cured Wolfram syndrome in mice.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

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Personalised Medicine