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Function of protein involved in liver cancer discovered
The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
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Personalised Medicine
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Best targets for immunotherapy identified by new model
A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
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Researchers discover new pathway to treat Ewing sarcoma
A study has demonstrated that blocking certain receptors in mice reduced Ewing sarcoma growth and metastasis, which could be used within future treatments.
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Whole genome sequencing could be used to improve cancer treatments
Researchers have used whole genome sequencing to analyse breast cancers and reveal which are more responsive to treatments, which could improve the development of oncologic therapies.
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Methodology developed to genetically modify lab mice and human cells
A method designed to genetically alter laboratory mice can also be used to produce personalised animal models of an aggressive type of malignant brain cancer in children.
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The elegant parallel of using CRISPR to understand disease mechanisms
CRISPR is the buzzword of the moment in the drug discovery industry – mainly due to its potential to correct disease-causing mutations. However, those using the technology need to be mindful that it is used responsibly, and possible risks are considered before use. Mark Behlke discusses the potential of CRISPR…
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New model found to improve drug development in pre-clinical trials
Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
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First blood-brain barrier chip using stem cells developed
Researchers have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells.
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MS treatment potential after condition-causing genes identified
Researchers have found 12 genes which cause MS, creating potential for preventative treatment of the condition.
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EU conditional marketing authorisation announced for ZYNTEGLO
ZYNTEGLO™ is the first gene therapy approved for transfusion-dependent β-thalassemia (TDT).
webinar
A high-throughput approach to developing T-cell immunotherapies
23 May 2019 | By Sartorius
Join us as we discuss the promises and pitfalls associated with developing individualised antigen-specific T-cell therapy products for clinical use.
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Novel findings could improve vaccinations against STIs
Researchers have shown how skin vaccinations could be used as a vaccination strategy for sexually transmitted infections (STIs).
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WINTHER trial yields promising results
Comprehensive tumour profiling promises new therapeutic options for patients with advanced cancer.
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Paving the path towards precision medicine
A method to view the immune cell 'landscape' of bowel cancer tumours could pave the way towards more individualised medicine and treatment...
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Tailoring treatment for acute myeloid leukaemia
Rapid drug response screening for leukaemia stem cells offers clues to relapse and to improving patient-specific therapies...
