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Under the microscope: Choosing the best microplate reader
Efficient microplate readers play an important role in effective hit molecule discovery. Mark Wigglesworth, of AstraZeneca, explains what he looks for in this technology.
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Personalised Medicine
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Extracellular vesicles could be personalised drug delivery vehicles
Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...
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Pro72Arg gene variant increases tumour cell metabolism
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
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Charles River Laboratories announces new tumour model compendium
The Compendium provides scientists an online resource to help design efficient in vitro and in vivo oncology research studies.
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Neural stem cell treatment may offer relief for MS
Scientists have shown that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by MS...
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Gene manipulation holds the key to personalised medicine
Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...
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Raman imaging technique shows Alzheimer’s disease progress in the brain
Using Raman optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease...
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Scientists coax human stem cells to become sensory interneurons
A new protocol could be a step toward stem cell-based therapies to restore sensation in people who have lost feeling in parts of their body...
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APC-mimetic scaffolds could facilitate more effective precision immunotherapies
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
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Quorum-sensing inhibitors may improve treatments for cystic fibrosis patients
Researchers have identified a promising solution to improving treatments offered to patients with cystic fibrosis that could lead to the development of new personalised therapies...
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Application note: KingFisher sample purification system
Next generation sequencing sample preparation on the KingFisher platform...
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New weakness found in most common childhood malignant brain tumour
A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
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An interview with Bjorg K. Hunter, Device Engineering Manager from GSK ahead of Pre-Filled Syringes Europe 2018
A debate on the impact of PFS regulation at Pre-Filled Syringes 2018...
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Metabolism can be used to subtype hepatoblastoma
Scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma...
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Therapy proves effective in subgroup of COPD patients
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...