news
New brain organoids express proteins in a human brain-specific manner
Culture conditions during embryoid body formation can be enhanced to gain glia-associated proteins and neural network activity.
List view / Grid view
Protein Expression
news
How hematopoietic stem cells retain their regenerative potential
Researchers found that genetic depletion of cyclophilin A results in stem cells distinctively lacking intrinsically disordered proteins.
news
FGF2 and SOX17 enable more efficient stem cell differentiation
The discovery of two proteins that effectively mature hiPSCs into endothelial cells may have a range of research and clinical benefits.
news
The first core regulatory circuit identified for ALCL
New understanding of the CRC and its interaction with STAT3 could lead to novel therapeutics and combination strategies.
news
Potential for targeted therapies based on the gigaxonin pathway
Researchers have discovered that higher expression of gigaxonin suppresses aggressive growth of human head and neck cancer cells.
whitepaper
Application note: Solutions for your protein sample preparation workflow challenges
Researchers often encounter common problems during protein sample preparation which can compromise the quality and quantity of protein obtained. Explore our solutions to these common challenges, including sample handling, storage and preparation method issues.
article
Protein offers promise for treatment of reproductive conditions
Scientists found that CXCR4 protein expression outside of the uterus is important for pregnancy maintenance.
news
MSK1’s importance for cognitive benefits
New study uncovers role of a neuronal protein kinase called mitogen- and stress-activated protein kinase 1 (MSK1) in mediating the cognitive benefits of environmental enrichment.
news
Newly discovered mechanism behind cognitive decline in aging
US researchers say new mechanism could lead to new drugs and therapies to treat normal cognitive decline in aging.
news
Alcohol-associated liver disease linked to abnormal splicing deregulation
Splicing deregulation is potential drug target and diagnostic tool, but can be affected by alcohol consumption and thus chronic liver disease.
news
Are female mice better protected against obesity?
The University of California underwent a mouse study disclosing underlying sex differences in mice for obesity.
news
Viruses can cause brain cells to fuse leading to a malfunctioning CNS
Researchers from Australia explore how viruses can alter brain cells, and thus the functions of our nervous system, leading to neurological symptoms.
news
Ancient virus holds connections to ALS in people
US study identifies promising new target, in protein remnants from an ancient virus, for treating underlying cause of ALS.
article
Targeting the immunotherapy potential of cytokines IL-12 and IL-18 with new advancements in protein engineering
In this article Dr Raymond Winquist, Oncology Fellow at Alkermes, covers the longstanding research challenges associated with cytokines: IL-12 and IL-18, and their untapped potential in immunotherapy and immuno-oncology.
news
Targeted therapy for treatment-resistant breast cancer
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.