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Research into cellular signalling mechanisms may lead to new treatments
Wnt moves to specific areas of the cell membrane, interacting with a receptor known as Ror2, and inducing the formation of a cytoneme...
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Protein Expression
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Key role of PI3Ky in Chagas disease described
The expression of PI3Ky increases during infection by T.cruzi, providing an essential response controlling the parasite and avoiding inflammation...
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How does Parkinson’s disease develop?
Study raises doubts on a previous theory of Parkinson’s disease...
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SMCHD1 protein found essential to X chromosome inactivation
The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...
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Blood test rapidly detects signs of pancreatic cancer
A new diagnostic test developed by researchers at UC San Diego shows promise for detecting pancreatic cancer earlier...
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Double-bridged peptides bind any disease target
Researchers have developed a new peptide format that they call double-bridged peptides...
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Blood test may predict future risk of cardiovascular events
A study of 27,000 women finds that branched-chain amino acid levels in the bloodstream are as predictive of heart disease as LDL cholesterol, other risk factors...
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Modified PIP protein differentiates between cancerous and non-cancerous cells
A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
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Scientists create complex transmembrane proteins from scratch
Advance paves the way for the design of transmembrane proteins with useful new functions...
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Researchers evaluate tau phosphorylation related targets for Alzheimer’s research
Scientists in Moscow have extended the reach of QSP modelling by applying it to tau phosphorylation to better understand Alzheimer’s disease (AD) progression.
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MeXis gene may protect against heart disease
Scientists have identified a gene that may play a protective role in preventing heart disease...
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Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
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Discovery lights path for Alzheimer’s research
Researchers identify binding site on the amyloid beta peptide that could facilitate better drugs to treat the disease...
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New genetic cause discovered for photosensitive blood disorder
Researchers have uncovered a new genetic cause for erythropoietic protoporphyria...
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Discovery improves understanding of cellular ageing and cancer development
A team of researchers has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, key players involved in cellular ageing.