news
New treatment target discovered for sleep apnoea
A recent study in mice revealed that an ion channel already proven to affect blood pressure in obese mice plays a role in suppressing their breathing, influencing sleep apnoea.
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Protein
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Simcere receives clearance to investigate a bi-functional fusion protein drug
The FDA has cleared the Simcere's investigational new drug application for SIM0237, an anti-PD-L1/IL-15 bi-functional fusion protein, for the treatment of adult patients with advanced solid tumours.
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Newly discovered GPCR signalling process opens possibility for novel therapies
US researchers have found that G protein-coupled receptors function in a way not previously known, which suggests untapped potential.
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New method to label proteins could help track disease
Scientists have developed a new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer.
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3D map reveals DNA organisation within human retina cells
Scientists shed light on how genetic architecture in human retina cells determine gene expression, tissue-specific function, and disease phenotype in blinding diseases.
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Mapped protein structure of Hepatitis C could lead to vaccine
Scripps scientists have mapped the protein structure of the Hepatitis C virus, paving the way for an effective vaccine.
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Study finds protein H84T-BanLec is effective against all known coronaviruses and influenzas
H84T-BanLec has viral-blocking abilities by binding to polysaccharides that are present on the surface of the viruses.
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New study reveals the exact molecular structure of an IgM-type B-cell receptor
Using cryo-EM, the researchers found that the B-cell receptor interacts with further receptors, thus controlling its signal transduction.
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Target for possible osteoarthritis treatment found in RORβ protein
A new study has revealed that activating the RORβ protein could lead to a possible treatment and prevention for osteoarthritis.
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Protein-based therapy shows promise for individuals with ALS
In a petri dish under an environmental condition reminiscent of ALS, the team found that the protein activates a unique pathway inside cells that increases survival and protects endothelial cells from toxic substances in the blood.
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New study highlights how to deliver a protein to the brain quickly
Potential uses for the study could include repairing spinal cord injuries and a range of other localised injection applications.
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Researchers have developed a drug that can break through the mucus barrier
A capsule that tunnels through mucus in the gastrointestinal tract could be used to orally administer large protein drugs such as insulin.
news
Newly discovered protein could be used to produce life-saving antifungals
Researchers have discovered a protein, Ait1, that is responsible for controlling cell growth in yeasts. Since humans and yeasts have remarkably similar cellular mechanisms, teasing out the differences presents drug developers with new target.
whitepaper
Product hub: Targeted protein degradation – next-generation therapeutics
Helen Harrison, Director of Screening at Amphista Therapeutics, discusses targeted protein degradation (TPD) and the discovery of drugs in this area.
whitepaper
Product hub: Uncover spatial biology secrets. Gain disease insights.
Discover why the Hyperion+ Imaging System is the standard to assess tumour-immune interactions and get deep single-cell insights.
