List view / Grid view
The FDA has cleared the Simcere's investigational new drug application for SIM0237, an anti-PD-L1/IL-15 bi-functional fusion protein, for the treatment of adult patients with advanced solid tumours.
US researchers have found that G protein-coupled receptors function in a way not previously known, which suggests untapped potential.
Scientists have developed a new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer.
Scientists shed light on how genetic architecture in human retina cells determine gene expression, tissue-specific function, and disease phenotype in blinding diseases.
Scripps scientists have mapped the protein structure of the Hepatitis C virus, paving the way for an effective vaccine.
H84T-BanLec has viral-blocking abilities by binding to polysaccharides that are present on the surface of the viruses.
Using cryo-EM, the researchers found that the B-cell receptor interacts with further receptors, thus controlling its signal transduction.
A new study has revealed that activating the RORβ protein could lead to a possible treatment and prevention for osteoarthritis.
In a petri dish under an environmental condition reminiscent of ALS, the team found that the protein activates a unique pathway inside cells that increases survival and protects endothelial cells from toxic substances in the blood.
Potential uses for the study could include repairing spinal cord injuries and a range of other localised injection applications.
A capsule that tunnels through mucus in the gastrointestinal tract could be used to orally administer large protein drugs such as insulin.
Researchers have discovered a protein, Ait1, that is responsible for controlling cell growth in yeasts. Since humans and yeasts have remarkably similar cellular mechanisms, teasing out the differences presents drug developers with new target.
Helen Harrison, Director of Screening at Amphista Therapeutics, discusses targeted protein degradation (TPD) and the discovery of drugs in this area.
Discover why the Hyperion+ Imaging System is the standard to assess tumour-immune interactions and get deep single-cell insights.
Discover all the ways you can harness ultrasensitive immunoassays to stay at the forefront of neuroscience research.
