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Sino Biological deposits recombinant Omicron proteins and antibodies to BEI Resources

14 January 2022 | By Sino Biological Inc.

To support disease research, Sino Biological has deposited reagents for the Omicron variant to BEI Resources.

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Product hub: Introducing the latest addition to Thermo Fisher Scientific’s genome editing portfolio – Invitrogen^TM TrueCut^TM HiFi Cas9 Protein!

6 January 2022 | By Thermo Fisher Scientific – Cell Biology

Read about the latest addition Invitrogen™ TrueCut™ HiFi Cas9 Protein to support your application and research goals.

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Product hub: Stay at the forefront of neuroscience research

16 December 2021 | By Merck KGaA

Read about our comprehensive portfolio of rigorously developed kits harnessing the ultrasensitive Single Molecule Counting (SMC™) technology.

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Application note: Competitive high-throughput analysis of kinase inhibitor binding kinetics

16 December 2021 | By BMG Labtech GmbH

A microplate-based method for the determination of association and dissociation rate values in high throughput using a kinetic probe competition assay (kPCA).

Close-up of man's knee with bone highlighted in red

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Common antioxidant reduces osteoarthritis markers in knee cartilage cells

16 December 2021 | By Anna Begley (Drug Target Review)

Gallic acid was found to decrease arthritis inflammation markers and improve the production of desired proteins in arthritic knee cells.

Pills and stethoscope on blackboard with COVID-19 structure written on it

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New platform screens for specific class of coronavirus antiviral compounds

15 December 2021 | By Anna Begley (Drug Target Review)

Researchers developed a platform that can rapidly screen thousands of compounds to identify potential antiviral drugs to treat coronaviruses.

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Nanobodies that bind a component of the SARS-CoV-2 replication complex

15 December 2021 | By Professor Gennaro Esposito (NYU Abu Dhabi), Professor Piergiorgio Percipalle (NYU Abu Dhabi)

Professors Piergiorgio Percipalle and Gennaro Esposito summarise their study which revealed two nanobodies that could inhibit a non-structural protein of SARS-CoV-2.

3D illustration of degradation of motor neuron

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Mechanism that causes ALS nerve destruction unveiled for first time

15 December 2021 | By Anna Begley (Drug Target Review)

The study reveals the biological mechanism that causes nerve destruction in amyotrophic lateral sclerosis (ALS), potentially leading to treatments that reverse the disease.

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Experimental enzyme treatment protects mice from lethal anthrax infection

9 December 2021 | By Anna Begley (Drug Target Review)

All mice infected with anthrax spores were completely protected after treatment with a pegylated enzyme known as PEG-CapD-CPS334C.

Older man with puzzle in shape of a brain

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HAT proteins could unveil new cancer and Alzheimer’s treatments

30 November 2021 | By Anna Begley (Drug Target Review)

The new study used cryo-electron microscopy to visualise the structure of a HAT protein and uncover compounds for drug development.

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“Sleeping” cancer cells could prevent tumour metastasis

25 November 2021 | By Anna Begley (Drug Target Review)

A new study prevented the growth of metastatic tumours in mice by forcing cancer cells into a dormant state, pointing to novel treatments.

Woman with arthritus holding hand highlighted in red

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Rheumatoid arthritis discovery may lead to novel inflammation blockers

24 November 2021 | By Anna Begley (Drug Target Review)

A new study links tumour necrosis factor seen in rheumatoid arthritis with T cell dysfunction, potentially leading to new therapies.

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Antihypertensive drugs could treat cerebral small vessel disease

18 November 2021 | By Anna Begley (Drug Target Review)

The antihypertensive drug candesartan cilexetil reduced matrisomal protein accumulation in mice with cerebral small vessel disease.

Hand of Alzheimer's patient holding nurse's hand

news

Existing cancer drugs could become new Alzheimer’s treatments

17 November 2021 | By Anna Begley (Drug Target Review)

An experimental drug for liver cancer and Dasatinib, approved for chronic myeloid leukaemia could be repurposed to treat Alzheimer's disease.

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Nanoscale “computer” a pivotal step for precision medicine

16 November 2021 | By Anna Begley (Drug Target Review)

The study paves the way for the construction of complex nanoscale computers for the prevention and treatment of cancer and other diseases.

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