news AI method for generating new proteins could accelerate drug development 31 March 2021 | By Victoria Rees (Drug Target Review) A novel artificial intelligence (AI) technique called ProteinGAN has shown success at studying well known proteins to develop new ones.
whitepaper Product hub: A cost, time and labour-saving protein purification platform 31 March 2021 | By GenScript In February 2021, US biotech company GenScript launched an updated version of its semi-automated system, AmMag™ SA Plus.
news Antibody could be used in tooth regeneration therapy, study shows 30 March 2021 | By Victoria Rees (Drug Target Review) A mAb could be used in tooth regeneration therapy, after a single administration generated new teeth in mice and ferrets.
news Inhibiting IRE1α pathway could be novel therapeutic strategy for lupus 29 March 2021 | By Victoria Rees (Drug Target Review) A study has revealed that blocking a molecule called IRE1α could prevent the release of neutrophil extracellular traps in lupus pathogenesis.
news Aptamer inhibits SARS-CoV-2 with novel mechanism of action, study shows 29 March 2021 | By Victoria Rees (Drug Target Review) An aptamer that can bind a different part of SARS-CoV-2 than known inhibitors could enhance treatments against coronavirus mutations.
news First 3D images of Survival Motor Neuron complex visualised 25 March 2021 | By Victoria Rees (Drug Target Review) Researchers have imaged the entire Survival Motor Neuron complex using X-ray diffraction analysis, among other techniques.
news ‘Zinc finger’ gene therapy could help to treat Alzheimer’s disease 23 March 2021 | By Victoria Rees (Drug Target Review) Promising results have been shown in an animal model of Alzheimer's disease treated with zinc finger protein transcription factors.
news Rhesus macaque model of Alzheimer’s disease developed 19 March 2021 | By Victoria Rees (Drug Target Review) Scientists have developed a model of the early stages of Alzheimer's disease in rhesus macaques to better test new treatments.
news Team uses antibodies to tag disease-related proteins for destruction 19 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a technique utilising antibodies to tag disease-causing proteins, to treat the underlying causes of disease.
news Method for analysing sugar-protein interactions could enable better biologics 17 March 2021 | By Victoria Rees (Drug Target Review) A novel machine learning method can explain how glycans stabilise proteins, aiding the discovery and design of protein-based drugs.
news New tool designed to add or remove sugar from proteins shows success 12 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a new tool that can add or remove sugar from proteins, which could be used to treat currently "undruggable" targets.
news Mosquito protein could hold key to therapeutics against flaviviruses 11 March 2021 | By Victoria Rees (Drug Target Review) A study has shown the mosquito protein AEG12 inhibits flaviviruses, the family of viruses that cause yellow fever, dengue and Zika.
news Study shows role IgM antibodies play in preventing thrombosis 10 March 2021 | By Victoria Rees (Drug Target Review) A new study has revealed that immunoglobulin-M antibodies recognise microvesicles, which are critical for the progression of thrombosis.
news Analysis of proteomic data reveals potential therapeutic targets for cancer 8 March 2021 | By Victoria Rees (Drug Target Review) Researches have provided a proof-of-concept that proteomic analysis could be used to identify drivers of aggressive cancers.
news Researchers identify antibodies with potent effects against malaria 8 March 2021 | By Victoria Rees (Drug Target Review) Six antibodies specific to the circumsporozoite protein of the malaria parasite have shown promise as therapeutic interventions, a study has shown.
