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Protein

news

Targeting Ku70 could improve bowel cancer treatment

29 January 2024 | By Drug Target Review

The Ku70 protein prevents cancer cells from becoming more aggressive and metastasising. It could also be used as an immune biomarker.

article

SARS-CoV-2: advancing the production of the ACE2 protein

26 January 2024 | By Ellen Capon (Drug Target Review)

Producing functional human ACE2 protein in mouse cells provides a new way to study the receptor used by the SARS-CoV-2 spike protein.

news

The potential of PD-L2 inhibitors for cancer treatment

24 January 2024 | By Drug Target Review

Researchers discover that blocking PD-L2 in senescent cells increases the efficacy of chemotherapy in mouse models.

news

Studying the effects of 3D genome organisation on gene silencing

19 January 2024 | By Drug Target Review

Researchers explored the effects of loops and 3D genome organisation on gene silencing, and found that ‘cohesinopathies’ may be linked it.

news

Using proteomics to predict long-term disability outcomes in MS

10 January 2024 | By Drug Target Review

Data from protein analyses, combined with data from patient journals, enabled the discovery of proteins that predict disease progression.

whitepaper

Article: Tips and Tricks for Leveraging Advanced Flow Cytometry

9 January 2024 | By Sartorius iQue®

Tips and tricks for fully leveraging Advanced Flow Cytometry.

whitepaper

Application note: Direct and Competitive Live Cell Antibody Binding

9 January 2024 | By Sartorius

Utilizing Advanced High-Throughput Flow Cytometry to Quantify Direct and Competitive Live Cell Antibody Binding

news

Controlling MYC’s hyperactivity with a peptide compound

8 January 2024 | By Drug Target Review

A novel peptide can suppress MYC by binding directly to it with sub-micro-molar affinity, advancing cancer drug development.

article

Unique self-activating proteins for drug discovery

8 January 2024 | By Drug Target Review

Explore cutting-edge hit-to-lead insights through exclusive interviews and studies by leading experts in the field.

article

Allosteric control sites in KRAS protein found

5 January 2024 | By Ellen Capon (Drug Target Review)

The first complete control map for any protein has been made for KRAS, and four potential drug targets have been discovered.

news

The loading mechanism of bacteria injectisomes is now understood

5 January 2024 | By Drug Target Review

Proximity labelling and single-particle tracking demonstrated that effectors in bacteria bind to mobile injectisome components.

news

New technology to effectively regulate gene expression

3 January 2024 | By Drug Target Review

A new strategy enables researchers to be more precise in the control of gene expression of a therapeutic protein.

news

How pathological alpha synuclein causes neuron death

20 December 2023 | By Drug Target Review

A new finding that pathological alpha-synuclein causes cells to increase protein synthesis suggests new targets for treating PD.

news

AI system produces binding proteins using limited target information

20 December 2023 | By Drug Target Review

New software can make protein molecules that bind with high affinity and specificity to many biomarkers, including human hormones.

news

Potential therapeutic target found for the Zika virus

12 December 2023 | By Drug Target Review

A discovery about Zika’s enzyme, NS2B-NS3, offers promise for therapeutic targets for Zika and other flaviviruses.

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Protein