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Collaborative enzyme study could lead to a target for cancer therapeutics
A new study into the enzyme Cdc34 may make it possible to target the enzyme specifically to develop new cancer therapeutics.
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Platform may find new options for mental health treatment
A drug discovery platform for mental health treatment could also help to identify mechanisms for the treatment of substance use disorders.
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Method developed for quicker and simpler production of lipidated proteins
A simple and direct method of introducing lipids into protein has been developed using palladium as a catalyst.
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Cancer-suppressing cells identified in pancreatic cancer
Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
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3D tissue models of brain tumours created in brain-mimicking environment
A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
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New therapeutic target identified for pulmonary fibrosis
A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
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Best targets for immunotherapy identified by new model
A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
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Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
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Gene therapy for DMD safely preserves muscle function
Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.
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New technology invented to streamline drug discovery
New protein-painting technology could lead to developing cancer immunotherapy medicines that can be administered as a pill.
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New compound keeps cells alive and functioning in a healthy state
A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.
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Antibodies used to treat and reverse MS symptoms in mice
Researchers have identified a protein on the surface of cells that cause MS and have used antibodies as an effective treatment for the condition in mice.
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Protein receptor linked to cell death imaged for the first time
Researchers have imaged an inflammation-related protein receptor on cell membranes which could inform future drug designs to prevent cell death.
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Potential treatment for heart attacks discovered by researchers
Researchers have uncovered a treatment that may be used to treat heart attacks or to prevent heart failure, using the circadian clock.
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Researchers discover new pathway to treat Ewing sarcoma
A study has demonstrated that blocking certain receptors in mice reduced Ewing sarcoma growth and metastasis, which could be used within future treatments.