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Drug candidate offers hope of vocal improvement for ADNP syndrome
Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.
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Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
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Swarm of exosomes protect against inhaled bacteria
A swarm of billions of exosomes armed with proteins has been shown to assist in the fight against bacteria inhaled through the nose...
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NGLY1 protein identified as potential target for melanoma treatment
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
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Chromatin study unearths link between DNA-protein binding and cancer
A team of scientists led by Stanford University School of Medicine has identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes.
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Intriguing egg protein behaviour may shape fertility and cancer treatment
Scientists in the U.S. have published their findings about the behaviour of proteins in mouse eggs, projecting possible impacts on infertility and cancer treatment.
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Protein sequencing method could transform biological research
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
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Atg2 tethers pre-autophagosomal membranes to endoplasmic reticulum
Researchers at Tokyo University have investigated the role of the Atg2 protein in the process of autophagy to aid drug discovery into neurodegeneration...
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Single molecule fluorosequencing to transform biological research
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
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Critical cancer immunity genes identified using genetic barcoding
Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...
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Immunotherapy targeting blood protein fibrin
Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...
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Alpaca immune system reveals a potential treatment for cancer
Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...
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PSD-95 molecule reveal potential treatment for stroke patients
A novel hybrid approach has revealed a 3D structure of a protein fragment that could serve as a drug target in treating stroke patients...
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Mass spectrometry and drug development – how the two come together
Since the development of the so-called soft ionisation techniques: electrospray ionisation and matrix-assisted laser desorption and ionisation in the 1980s and early 1990s and the development of high-resolution mass spectrometers, mass spectrometry (MS) has come to the fore in studying complex biological systems...
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Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...