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SAMHD1 enzyme may block HIV disease progression
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works...
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Protein
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IPSE protein has potential to alleviate debilitating disease
Chemotherapy-induced hemorrhagic cystitis alleviated by a protein that parasites use to keep hosts alive...
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Study changes long-held concepts of cell decoding
NIH scientists discover macromolecular complexes that could enable medication development...
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KIF5A gene associated with the development of ALS
An international team of researchers has identified a new gene associated with the development of amyotrophic lateral sclerosis...
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MVP found to be consequential in 16p11.2 deletion syndrome
Neuroscientists have identified a specific molecular mechanism that appears to undermine the ability of neurons to properly incorporate changes driven by experience...
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Application note: Simultaneous dual phosphoprotein target analysis with Alpha Terbium SureFire Ultra Multiplex
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
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PARK14 protein associated with inflammation in Parkinson’s
Study overturns previous ideas about enzyme linked to many illnesses
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Researchers identify key step in viral replication
Researchers have showed how a common virus hijacks a host cell’s protein to help assemble new viruses before they are released.
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
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Modified PIP protein differentiates between cancerous and non-cancerous cells
A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
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EGFL7 protein provides a new treatment approach for MS
Researchers have discovered that the EGFL7 protein inhibits the migration of immune cells into the brain...
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Preventing exhaustion in immune cells boosts immunotherapy in mice
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
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Scientists create complex transmembrane proteins from scratch
Advance paves the way for the design of transmembrane proteins with useful new functions...
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Pro72Arg gene variant increases tumour cell metabolism
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
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Tempol provides a potential treatment for Chuvash polycythemia
A study in mice suggests that experimental drug may be effective against mountain sickness and other polycythemias...