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GAPSA reveals new HIV targets
Researchers have developed the first-ever high-throughput, genome-scale imaging-based approach to investigate protein stability...
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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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Antibodies provide potential targets for RSV vaccine development
Scientists have found and characterised the activity of four antibodies produced by the human immune system that targets an important protein found in the respiratory syncytial virus...
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MiR-223 could help treat cancer and asthma
A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer...
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New insights into alpha-synuclein function holds promise for Parkinson’s treatment
Researchers have gained important insights into the role of alpha-synuclein – the protein associated with Parkinson’s disease – in nerve cells and how calcium affects its function. This knowledge is hoped to better arm scientists regarding future treatment for the disease.
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MeXis gene may protect against heart disease
Scientists have identified a gene that may play a protective role in preventing heart disease...
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Small molecule could make a big difference for arthritis patients
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
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CpAM molecules advance fight against hepatitis B
Researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer...
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LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
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TIMP-1 protein plays role in reducing cancer’s spread
Researchers have found that the TIMP-1 molecule that helps regulate gene expression plays a big role in keeping us safe from the machinations of cancer...
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Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
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Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.
whitepaper
Whitepaper: Phenotypic drug discovery with high content screening
Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.
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Energy storehouses in the brain may be source of Alzheimer’s
Research into the effects of Alzheimer’s disease on how mitochondria structures function has revealed that a highly toxic beta amyloid protein disrupts normal function.
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New study suggests possible marker to test patient immunotherapy benefit
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments.