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Small molecule could make a big difference for arthritis patients
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
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CpAM molecules advance fight against hepatitis B
Researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer...
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LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
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TIMP-1 protein plays role in reducing cancer’s spread
Researchers have found that the TIMP-1 molecule that helps regulate gene expression plays a big role in keeping us safe from the machinations of cancer...
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Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
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Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.
whitepaper
Whitepaper: Phenotypic drug discovery with high content screening
Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.
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Energy storehouses in the brain may be source of Alzheimer’s
Research into the effects of Alzheimer’s disease on how mitochondria structures function has revealed that a highly toxic beta amyloid protein disrupts normal function.
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New study suggests possible marker to test patient immunotherapy benefit
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments.
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G-CSF protein involved in cocaine addiction
Researchers have identified a protein produced by the immune system that could be responsible for the development of cocaine addiction...
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Study reveals how MRSA infection compromises lymphatic function
MRSA infection impairs the ability of lymphatic vessels to pump lymphatic fluid to lymph nodes in mouse models, which may contribute to the frequent recurrences of MRSA infection experienced by patients.
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The combination of two proteins exerts a regenerating effect in Parkinson’s disease
Parkinson’s research has led to the development an experimental model that allows different stages of Parkinson’s disease to be reproduced.
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Human protein may aid neuron invasion by virus that causes hand, foot, and mouth disease
A human protein known as prohibitin may play a significant role in infection of the nervous system by EV71, one of several viruses that can cause hand, foot, and mouth disease.
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NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
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Scientists identify potential therapeutic target for HER2-driven breast cancer
Researchers have made a unique discovery about the role of the MED1 protein in breast cancer formation, showing it to be a promising therapeutic target worthy of future study.
