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The future for quality control of mRNA medications

16 February 2023 | By Izzy Wood (Drug Target Review)

Japanese researchers combine cutting edge mass spectrometry with software analysis to elucidate mRNA structure.

article

Understanding molecular mechanisms behind breast cancer

15 February 2023 | By Fraser Owen (Drug Target Review)

Oestrogen receptors play a crucial role in breast cancer. By making them therapeutic targets, oestrogen can be regulated with the aim to prevent breast cancer.

article

Latest in lab automation

9 February 2023 | By Izzy Wood (Drug Target Review)

In this article Drug Target Review's Izzy Wood highlights three of the latest findings using lab automation techniques and technologies that aid scientists.

Coronavirus COVID-19 under the microscope. 3d illustration

news

Researchers discover small molecules that bind to SARS-CoV-2 spike proteins

8 February 2023 | By Ria Kakkad (Drug Target Review)

The resulting compounds, which can bind to spike proteins from the original coronavirus, could serve as a starting point for developing broad-spectrum treatments for COVID-19.

article

Ovarian cancer breakthrough: the potential of rhenium tricarbonyl (TRIP) as a promising anti-tumour drug

8 February 2023 | By Izzy Wood (Drug Target Review)

In this exclusive article, Drug Target Review’s Izzy Wood highlights ground-breaking ovarian cancer research, after speaking with Dr Benjamin Neuditschko, from the Institute Krems Bioanalytics at IMC Krems.

news

What do cancer cells crave?

7 February 2023 | By Izzy Wood (Drug Target Review)

US researchers uncover the amino acid: arginine, that prompts genetic mutations in cancer cells.

news

Experimental antidepressant could also treat alcohol use disorder

3 February 2023 | By Izzy Wood (Drug Target Review)

A US pre-clinical study investigating the antidepressant: MAP4343, discovered it reduced alcohol intake in a mouse model of alcoholism.

news

Measles virus can develop mutations that cause fatal SSPE

2 February 2023 | By Izzy Wood (Drug Target Review)

Japanese researchers find a new mechanism for how the measles virus can cause a rare but fatal neurological disorder: subacute sclerosing panencephalitis (SSPE).

webinar

Using integrative biophysical approaches to understand GPCR regulation by β-arrestins

30 January 2023 | By Thermo Fisher Scientific

Watch this webinar to learn how an integrated structural biology workflow can be used to get crucial structural insights on key protein targets that are of therapeutic interest.

news

Unexpected neuronal molecule makes prostate cancer more aggressive

24 January 2023 | By Izzy Wood (Drug Target Review)

US researchers discover a potential therapeutic avenue through the molecule NgR2, against an aggressive form of prostate cancer.

news

Novel therapeutic approach aims to prevent ARDS

19 January 2023 | By Izzy Wood (Drug Target Review)

UCLA researchers have found peptide blocks that cause the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.

news

Major lung cancer mechanism can be used to evade immune attack

17 January 2023 | By Izzy Wood (Drug Target Review)

US researchers found high levels of XBP1s in lung cancer cells, which plays a key part in regulating the local immune environment in lung tumours, and can be disabled to increase anti-cancer immunity

news

New database maps proteins that could predict cancer

17 January 2023 | By Izzy Wood (Drug Target Review)

Swedish researchers unveiled a new cancer protein profile database compiled from artificial intelligence and machine learning.

Pink Reddish eye due to viral, bacterial or allergic conjunctivitis icon isolated on pink background. Minimalism concept. 3d illustration 3D render

news

Study identifies gene and proteins that could treat dry eye disease

12 January 2023 | By Ria Kakkad (Drug Target Review)

Researchers found that proteins made by stem cells that regenerate the cornea could be new targets for treating dry eye disease.

article

Could drinking green tea, red wine and beer prevent Alzheimer’s?

11 January 2023 | By Izzy Wood (Drug Target Review)

In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.

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