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Proteomics

news

New AI tool accurately portrays metabolic states

2 September 2024 | By Drug Target Review

RENAISSANCE can quantify unknown intracellular metabolic states, including metabolic fluxes.

news

Identifying biomarkers for progressive supranuclear palsy

5 July 2024 | By Drug Target Review

Protein biomarkers in spinal fluid linked to PSP could enable earlier diagnosis and treatment for this neurological disorder.

news

Proteogenomics: finding targets for never-smoker lung cancer

3 June 2024 | By Drug Target Review

Through multi-omics analysis, researchers find that oestrogen signalling could be a target for never-smoker lung cancer cases.

article

Transomics’ impact on a promising liver cancer therapeutic

17 May 2024 | By Jon Hu (Pepper Bio)

Using its AI-driven platform, Pepper Bio discovered a promising therapeutic for liver cancer. In this Q&A session with Jon Hu, CEO and co-founder of Pepper Bio, we dive into how the identification of two inhibitors led to a $135M in-licensing deal.

whitepaper

Poster: Assays for DDX3, DDX5, DDX17, RIG-I, and MDA5

10 May 2024 | By BellBrook Labs

A panel of HTS assays was developed using the Transcreener platform to accelerate the development of selective helicase inhibitors.

whitepaper

Poster: Assays for PRMT5, MLL4, METTL3/14, & NSP14

7 May 2024 | By BellBrook Labs

AptaFluor SAH: A Homogenous, Universal Assay for Histone, RNA, & DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, & NSP14

news

Mitochondrial depletion results in abnormal protein accumulation

22 April 2024 | By Drug Target Review

Researchers find the mechanism which may underly the onset and progression of age-related neurodegenerative diseases.

news

Using omic data to develop and validate biomarkers of ageing

22 February 2024 | By Drug Target Review

Researchers highlight the need for considering biomarkers alongside other health outcomes, as well as the need for omic data standardisation.

news

Multi-omic approach classifies biomarkers for paediatric sepsis

8 February 2024 | By Drug Target Review

Researchers have discovered potential biomarkers to identify paediatric sepsis progression stage, enabling more targeted treatment.

whitepaper

Application Note: Understanding The Multiplex Imaging Landscape

1 February 2024 | By Leica Microsystems

Learn about the different types of multiplexed imaging available, as well as their applications, benefits and disadvantages.

whitepaper

Application note: In situ identification of cancer stem cell niches (HCC)

1 February 2024 | By Leica Microsystems

This app note explores a groundbreaking multiplex immunodetection approach to identify cancer stem cell niches within hepatocellular carcinoma (HCC).

whitepaper

Whitepaper: Targeting kinases in the innate immune response

24 January 2024 | By BellBrook Labs

The guide provides examples of how Transcreener allowed rapid assay development to enable screening for kinases in innate immune pathways.

news

Using proteomics to predict long-term disability outcomes in MS

10 January 2024 | By Drug Target Review

Data from protein analyses, combined with data from patient journals, enabled the discovery of proteins that predict disease progression.

article

A Guide to DNA Damage Response and Innate Immunity

10 January 2024 | By BellBrook Labs

In this guide, we provide an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets.

news

Discovery enables further investigation into new ligases

4 January 2024 | By Drug Target Review

Researchers have developed a new PROTAC that activates the protein degradation system and binds to a previously inaccessible ligase.

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Proteomics