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Proteomics

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Researchers link SARS-CoV-2 PLpro to COVID-19 symptoms

10 June 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that the SARS-CoV-2 PLpro cuts human proteins so could potentially cause a range of COVID-19 symptoms.

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Brochure: Neuroscience solutions

9 June 2021 | By PerkinElmer

Complete solutions for neurological disease research and discovery - helping you to better understand diseases to improve patient outcomes.

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SARS-CoV-2 “Mexican variant” sequence analysed by researchers

7 June 2021 | By Victoria Rees (Drug Target Review)

Analysis of one million SARS-CoV-2 genome sequences has revealed a new variant named T478K, spreading mostly in Mexico.

Application note: Western blot & IP assay to verify antibody specificity

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Application note: Western blot & IP assay to verify antibody specificity

1 June 2021 | By Bethyl Laboratories

Learn about a practical, high-throughput method for validating the target-specificity of antibodies for the application of western blot.

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Drug target to halt progression of Parkinson’s disease identified

28 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have shown that trapped LC3B protein in brain cells enables Parkinson's disease to spread, presenting a drug target.

Advantages of including untargeted and targeted metabolomics into drug development and clinical trials

webinar

Advantages of including untargeted and targeted metabolomics into drug development and clinical trials

25 May 2021 | By Metabolon

Discover how metabolomics can support your biomarker strategy in drug development and clinical trials in this on-demand webinar.

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Computational modelling reveals SARS-CoV-2 mutation ‘hotspots’

20 May 2021 | By Victoria Rees (Drug Target Review)

A new modelling method could be used as a surveillance tool to monitor emerging infectious SARS-CoV-2 variants, scientists say.

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Protein associated with Lyme disease arthritis discovered

14 May 2021 | By Victoria Rees (Drug Target Review)

A team has shown that the NapA protein, associated with Lyme disease, attracts inflammatory molecules in the body.

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ebook: Accelerate vaccine development

13 May 2021 | By Molecular Devices

Our comprehensive portfolio suite is designed to optimize your productivity to get safe and efficacious vaccines and therapeutics to market faster.

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New vaccine design developed to protect against Ebola virus

13 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have designed a new nanoparticle-based vaccine against Ebola that has shown promise in mice and rabbits.

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Second mechanism of action discovered for COVID-19 drug remdesivir

11 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that a metabolite of remdesivir potentially targets a SARS-CoV-2 protein involved in suppressing the host cell's defence response.

Cellular Thermal Shift Assays - bringing relevant target engagement to your drug discovery workflow

webinar

Cellular Thermal Shift Assays – bringing relevant target engagement to your drug discovery workflow

11 May 2021 | By PerkinElmer

Get the Big Picture and listen to Pharma thought leaders how they view CETSA® and its impact on their Drug Discovery.

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Computational epitope map of SARS-CoV-2 Spike protein developed

7 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have produced a computational simulation of the SARS-CoV-2 Spike protein, finding spots that glycans do not cover.

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Antibodies cover entirety of SARS-CoV-2 Spike protein, study shows

5 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that over 80 percent of antibodies target sections of the SARS-CoV-2 Spike protein other than the RBD.

ebook: Antibody detection for cancer research

whitepaper

ebook: Antibody detection for cancer research

3 May 2021 | By Bethyl Laboratories

Gain more insight into immune-tumor interactions and learn how antibody detection techniques like multiplexing is advancing immunotherapies.

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Proteomics