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BDNF protein could be key to preserving heart function in DMD
A protein known to drive nerve cell survival in the brain and spinal cord may also protect failing hearts in children and young adults with DMD...
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Proteomics
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IgE protein may protect against skin cancer
The components of the immune system that trigger allergic reactions may also help protect the skin against cancer, suggest new findings...
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Study pinpoints the ‘Big Bang’ of tau-induced Alzheimer’s neurodegeneration
Scientists in the U.S. have identified what they believe to be the genesis of Alzheimer's disease – the precise point at which a healthy tau protein becomes toxic but has not yet formed deadly tangles in the brain. The finding opens up numerous avenues for treatment research.
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Novel drug therapy partially restores hearing in mice
A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD).
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CLR01 protein found in semen increases the spread of Ebola virus infection
Penn study suggests that targeting amyloid fibrils could prevent sexual transmission...
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NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
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Breast cancer could be prevented by targeting epigenetic proteins
Researchers have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone.
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Eosinophilic esophagitis may be due to missing SPINK7 protein
NIH-funded study finds replacement therapy reversed effects in tissue experiments...
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SMCHD1 protein found essential to X chromosome inactivation
The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...
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Scientists create ‘genetic atlas’ of proteins in human blood
Researchers have created the first detailed genetic map of human proteins...
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Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.
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Researchers use blood serum markers to develop lupus risk index
Researchers have developed an index that identifies the risk for lupus based on the presence and amount of IgG and IgM antibodies and levels of C1q...
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Tau mutations may increase cancer risk
Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...
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Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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CHRNA2 receptor proteins may help fat cells burn energy
The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells...